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ARPC4 and RNF130
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
ARPC4
RNF130
Gene Name
actin related protein 2/3 complex, subunit 4, 20kDa
ring finger protein 130
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Arp2/3 Protein Complex
Cell Projection
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Integral Component Of Membrane
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Enzyme Binding
Protein Binding, Bridging
Actin Filament Binding
Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Ligase Activity
Biological Process
Axon Guidance
Actin Filament Polymerization
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Actin Nucleation
Innate Immune Response
Ephrin Receptor Signaling Pathway
Apoptotic Process
Programmed Cell Death
Protein Ubiquitination
Pathways
EPHB-mediated forward signaling
Axon guidance
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Coronary heart disease (
21347282
)
Protein-Protein Interactions
10 interactors:
ACTR2
ACTR3
ARPC1B
ARPC2
ARPC3
ARPC5
ARPC5L
NELFCD
PNMA5
RNF130
13 interactors:
ARPC4
FGFR3
SCN2A
TGFBR1
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2N
UBE2Z
Entrez ID
10093
55819
HPRD ID
10368
11504
Ensembl ID
ENSG00000241553
ENSG00000113269
Uniprot IDs
P59998
J3KN31
Q2HIY3
Q59EL1
Q86XS8
PDB IDs
Enriched GO Terms of Interacting Partners
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Arp2/3 Complex-mediated Actin Nucleation
Actin Nucleation
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Positive Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Polymerization
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Actin Filament Organization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cellular Component Size
Regulation Of Protein Complex Assembly
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Regulation Of Cytoskeleton Organization
Ephrin Receptor Signaling Pathway
Actin Cytoskeleton Organization
Actin Filament-based Process
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Organelle Organization
Phagocytosis
Fc Receptor Signaling Pathway
Cytoskeleton Organization
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Axon Guidance
Meiotic Chromosome Movement Towards Spindle Pole
Immune Response-regulating Signaling Pathway
Axonogenesis
Axon Development
Asymmetric Cell Division
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Cellular Component Organization
Chemotaxis
Positive Regulation Of Immune Response
Neuron Projection Morphogenesis
Endocytosis
Meiotic Cytokinesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Innate Immune Response
Movement Of Cell Or Subcellular Component
Neuron Projection Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Regulation Of Immune Response
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor 4 Signaling Pathway
Regulation Of Protein Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Immune Response-regulating Signaling Pathway
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Activation Of Innate Immune Response
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cellular Protein Modification Process
Regulation Of DNA-templated Transcription In Response To Stress
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Innate Immune Response
Regulation Of Immune Response
Regulation Of Ubiquitin-protein Transferase Activity
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Innate Immune Response
Modification-dependent Protein Catabolic Process
Cellular Response To Hypoxia
Protein K11-linked Ubiquitination
Cellular Response To Decreased Oxygen Levels
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Transferase Activity
Cellular Protein Catabolic Process
Cellular Response To Oxygen Levels
Protein Catabolic Process
Cellular Protein Metabolic Process
Positive Regulation Of Immune Response
Protein K63-linked Ubiquitination
Transforming Growth Factor Beta Receptor Signaling Pathway
Immune Response
Regulation Of Immune System Process
Negative Regulation Of Mitotic Nuclear Division
Defense Response
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Negative Regulation Of Cell Cycle
Cellular Macromolecule Catabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Enzyme Linked Receptor Protein Signaling Pathway
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