MYSM1 and HOOK1

		MYSM1	HOOK1
Description		Myb like, SWIRM and MPN domains 1	hook microtubule tethering protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Protein-containing Complex	Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton HOPS Complex FHF Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Histone Binding Metal Ion Binding Metal-dependent Deubiquitinase Activity Histone H2A Deubiquitinase Activity	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Immune System Process Chromatin Organization Chromatin Remodeling Proteolysis Regulation Of Cell Migration Pigmentation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Hair Follicle Development Regulation Of Hemopoiesis	Golgi Organization Endosome Organization Lysosome Organization Spermatogenesis Spermatid Development Endosome To Lysosome Transport Protein Transport Cell Differentiation Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly Protein Localization To Perinuclear Region Of Cytoplasm
Pathways		Metalloprotease DUBs
Drugs
Diseases
GWAS		Diabetic retinopathy ( 21310492) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		3 interacting genes: H2AC20 MPP7 STING1	46 interacting genes: AKTIP ANK3 ANKRD23 AP1M1 AP4M1 CCDC9 CDC5L CDK4 CUL1 CWF19L2 DENND1B ESS2 EXOSC7 FAM161A FHIP1B HNRNPLL HOOK2 HOOK3 KAT5 LENG1 LMO2 MEOX2 PIAS2 PRPF6 RBM22 RNF10 RPS7 SNW1 TBC1D7 TFIP11 UNKL USP2 UTP14A UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80
Entrez ID		114803	51361
HPRD ID		13903	07428
Ensembl ID		ENSG00000162601	ENSG00000134709
Uniprot IDs		A0A590UJW2 Q5VVJ2	Q9UJC3
PDB IDs		2CU7 2DCE
Enriched GO Terms of Interacting Partners?		Signaling Adaptor Activity Cyclic-di-GMP Binding STING Complex 2',3'-cyclic GMP-AMP Binding Vacuole Organization FHF Complex Protein Localization To Adherens Junction MPP7-DLG1-LIN7 Complex Protein Localization To Perinuclear Region Of Cytoplasm Manchette Assembly Proton Channel Activity Positive Regulation Of CGAS/STING Signaling Pathway	HOPS Complex Endosome To Lysosome Transport Vacuolar Transport Lysosomal Transport FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Lysosome Organization Vacuole Organization Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Catalytic Step 2 Spliceosome Vesicle Organization Early Endosome To Late Endosome Transport MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Clathrin-coated Vesicle AP-3 Adaptor Complex Endosome Organization RNA Processing Regulation Of Transcription By RNA Polymerase II Lysosomal HOPS Complex Protein Transport Endosomal Transport Spliceosomal Complex MRNA Processing Establishment Of Protein Localization MRNA Metabolic Process Zinc Ion Binding RNA Splicing U2-type Catalytic Step 2 Spliceosome Vesicle-mediated Transport Nucleus Intracellular Transport Regulation Of Macromolecule Metabolic Process RNA Metabolic Process CORVET Complex Regulation Of Gene Expression Vesicle Fusion Regulation Of Metabolic Process Nuclear Speck Organelle Membrane Fusion Regulation Of DNA-templated Transcription Positive Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Localization Regulation Of Primary Metabolic Process Nucleic Acid Metabolic Process Protein Targeting To Vacuole Clathrin Adaptor Complex
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