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CHFR
Gene Name
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
PML Body
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Mitotic Cell Cycle Checkpoint
Modification-dependent Protein Catabolic Process
Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
26 interactors:
AURKA
BRD4
CBLC
EEF1G
GABBR1
HDAC1
HDAC2
HIST2H2AC
HIST2H2BE
ITGAE
PML
RNF125
RNF7
TRIM9
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2I
UBE2N
UBE2V1
UBE2W
WDR47
Entrez ID
55743
HPRD ID
05552
Ensembl ID
ENSG00000072609
Uniprot IDs
Q96EP1
PDB IDs
1LGP
1LGQ
2XOC
2XOY
2XOZ
2XP0
Enriched GO Terms of Interacting Partners
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Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Protein Metabolic Process
Protein Catabolic Process
Protein K11-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K63-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Protein Metabolic Process
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Cellular Response To Stress
Proteolysis
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Negative Regulation Of Cell Cycle
Activation Of Innate Immune Response
Catabolic Process
Innate Immune Response
Positive Regulation Of Innate Immune Response
Histone Modification
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Response To Stress
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of Innate Immune Response
Chromatin Organization
Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Regulation Of Response To DNA Damage Stimulus
Protein Monoubiquitination
Positive Regulation Of Proteolysis
Transforming Growth Factor Beta Receptor Signaling Pathway
ISG15-protein Conjugation
Cellular Response To DNA Damage Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Fungiform Papilla Formation
Regulation Of DNA-templated Transcription In Response To Stress
Chromatin Modification
Regulation Of Organelle Organization
Tagcloud
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adeno
adenocarcinoma
adenocarcinomas
alk
atlas
biomarker
correlates
datasets
egfr
erbb2
exon19
fgfr1
fgfr2
fgfr3
kras
nf1
pik3ca
powerful
predictor
project
ret
ros1
seq
squamous
stk11
taxane
tcga
tp53
utilized