SIK2

Gene Name		salt-inducible kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Phosphorylation Insulin Receptor Signaling Pathway Intracellular Signal Transduction Regulation Of Insulin Receptor Signaling Pathway Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: APP CRTC2 GABARAPL2 HDAC5 IRS1 VCP
Entrez ID		23235
HPRD ID		12348
Ensembl ID
Uniprot IDs		Q9H0K1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Cellular Biosynthetic Process Response To Stress Regulation Of Proteolysis Histone H3-K9 Acetylation Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Cellular Component Assembly Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Collateral Sprouting In Absence Of Injury Chemical Homeostasis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Metabolic Process Glucose Homeostasis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Insulin Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Regulation Of Catalytic Activity Cellular Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein Deubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hydrolase Activity Axon Choice Point Recognition Protein Hexamerization Protein Homooligomerization Regulation Of Binding Golgi Vesicle Transport Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Response To Insulin Positive Regulation Of Proteolysis Neuron Remodeling Cellular Response To Peptide Hormone Stimulus Aggresome Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Peptide Positive Regulation Of Fatty Acid Beta-oxidation Translesion Synthesis Positive Regulation Of Transcription, DNA-templated Defense Response Negative Regulation Of Proteolysis
Tagcloud ?		43delta abrogated adipocyte amp ampk autophagosome autophagosomes autophagy belonging coordinated deacetylation determinant elusive hdac6 hormones indispensable interplay k53q k53r lys lysosome mimetic nonacetylatable nutrients pool restores switch threonine uncover