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U2AF2 and HLA-DMA
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
U2AF2
HLA-DMA
Gene Name
U2 small nuclear RNA auxiliary factor 2
major histocompatibility complex, class II, DM alpha
Image
Gene Ontology Annotations
Cellular Component
Prp19 Complex
Nucleoplasm
Spliceosomal Complex
Nuclear Speck
Lysosomal Membrane
Multivesicular Body
Cell Surface
Membrane
Integral Component Of Membrane
Late Endosome Membrane
MHC Class II Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Nucleotide Binding
Protein Binding
Enzyme Binding
Poly(A) RNA Binding
C2H2 Zinc Finger Domain Binding
MHC Class II Protein Complex Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Processing
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Positive Regulation Of RNA Splicing
Negative Regulation Of MRNA Splicing, Via Spliceosome
Peptide Antigen Assembly With MHC Class II Protein Complex
Protein Transport
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Thymic T Cell Selection
Positive Regulation Of T Cell Differentiation
Inner Ear Development
Positive Regulation Of Immune Response
Chaperone Mediated Protein Folding Requiring Cofactor
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions
51 interactors:
AES
APBB1
ATXN1
BEND7
CCAR1
CHERP
CHIC2
CPSF7
DACH1
DDX17
DDX6
DPPA2
DVL2
EPB41
GEMIN2
GLIS2
HLA-DMA
HNRNPA0
HNRNPD
HNRNPK
IL7R
KHDRBS1
KHDRBS3
KIAA0907
LURAP1
MAP1B
PIN1
POLR2A
PRPF3
PRPF40A
PUF60
QKI
RBFOX2
RBM39
RBM4
SAP30BP
SCAF11
SF1
SMAD5
SNRPA
SRPK1
SRPK2
SRSF1
SRSF11
SUGP1
TCERG1
THAP1
TOP1
U2AF1
WT1
ZRSR2
8 interactors:
B3GAT1
CD74
CD82
HLA-DMB
HLA-DOA
HLA-DRA
HLA-DRB1
U2AF2
Entrez ID
11338
3108
HPRD ID
01872
00830
Ensembl ID
ENSG00000063244
ENSG00000204257
Uniprot IDs
P26368
Q31604
Q5SP00
Q6ICR9
PDB IDs
1JMT
1O0P
1OPI
1U2F
2G4B
2HZC
2M0G
2U2F
2YH0
2YH1
3VAF
3VAG
3VAH
3VAI
3VAJ
3VAK
3VAL
3VAM
4FXW
4I0P
Enriched GO Terms of Interacting Partners
?
RNA Processing
RNA Splicing
MRNA Processing
MRNA Metabolic Process
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Splicing, Via Transesterification Reactions
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Ribonucleoprotein Complex Assembly
Biosynthetic Process
Spliceosomal Complex Assembly
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Regulation Of MRNA Splicing, Via Spliceosome
Ribonucleoprotein Complex Biogenesis
Cellular Macromolecular Complex Assembly
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Metabolic Process
Regulation Of MRNA Processing
Termination Of RNA Polymerase II Transcription
Regulation Of MRNA Stability
Regulation Of RNA Stability
Cellular Process
DNA-templated Transcription, Termination
Regulation Of Translation
MRNA 3'-end Processing
Positive Regulation Of Macromolecule Biosynthetic Process
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Female Gonad Development
Circadian Regulation Of Translation
RNA 3'-end Processing
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Peptide Antigen Assembly With MHC Class II Protein Complex
MHC Class II Protein Complex Assembly
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation
Regulation Of T Cell Activation
Regulation Of Cell-cell Adhesion
Regulation Of Lymphocyte Activation
Regulation Of Cell Activation
Polysaccharide Assembly With MHC Class II Protein Complex
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Activation
Positive Regulation Of Cell Adhesion
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune Response
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Cellular Protein Complex Assembly
Protein Complex Assembly
Immune System Process
Negative Regulation Of Immune System Process
T Cell Costimulation
Cytokine-mediated Signaling Pathway
Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Macrophage Migration Inhibitory Factor Signaling Pathway
Negative Regulation Of T Cell Activation
Negative Regulation Of Leukocyte Cell-cell Adhesion
T Cell Receptor Signaling Pathway
Negative Regulation Of Homotypic Cell-cell Adhesion
Cellular Response To Cytokine Stimulus
Positive Regulation Of Lymphocyte Proliferation
Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Mononuclear Cell Proliferation
Regulation Of T Cell Differentiation
Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Receptor-mediated Signaling Pathway
Cellular Macromolecular Complex Assembly
Negative Regulation Of Lymphocyte Activation
Negative Regulation Of Cell-cell Adhesion
Cellular Response To Interferon-gamma
Regulation Of T Cell Proliferation
Response To Cytokine
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Negative Regulation Of Leukocyte Activation
Tagcloud
?
acceptor
accessory
advance
alters
codons
corroborated
cytidine
doi
junctions
leu
missense
november
novo
online
publication
q157
q157p
q157r
s34
s34f
s34y
seq
snrnp
speckles
splice
splicing
u2af1
uridine
Tagcloud (Difference)
?
acceptor
accessory
advance
alters
codons
corroborated
cytidine
doi
junctions
leu
missense
november
novo
online
publication
q157
q157p
q157r
s34
s34f
s34y
seq
snrnp
speckles
splice
splicing
u2af1
uridine
Tagcloud (Intersection)
?