U2AF2 and ZRSR2P1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		U2AF2	ZRSR2P1
Description		U2 small nuclear RNA auxiliary factor 2	ZRSR2 pseudogene 1
Image			No pdb structure
GO Annotations	Cellular Component	Commitment Complex Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Prespliceosome U2AF Complex	Nucleus Spliceosomal Complex U2AF Complex Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Enzyme Binding Pre-mRNA 3'-splice Site Binding C2H2 Zinc Finger Domain Binding Molecular Function Inhibitor Activity	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of Protein Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Protein hydroxylation
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Menopause (age at onset) ( 26414677)
Interacting Genes		71 interacting genes: - APBB1 ATXN1 BEND7 CCAR1 CDC42 CHIC2 CPSF7 DACH1 DDX6 DPPA2 DVL2 EPB41 FUBP1 GEMIN2 GLIS2 HLA-DMA HMBOX1 IL7R INO80B KHDC4 KHDRBS3 LURAP1 MAP1B MRPL15 NKAPD1 OGT OTUB2 PHF5A PIN1 POLR2A PRPF40A PUF60 QKI RBFOX2 RBM11 RBM39 RBM4 RBMY1F RBMY1J SAP30BP SCAF11 SF1 SF3B3 SF3B5 SF3B6 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SRSF3 STAC3 SUGP1 SUMO2 TCERG1 TCF23 THAP1 TLE5 TOP1 U2AF1 USP7 WT1 ZNF107 ZNF526 ZNF57 ZNF71 ZNF835 ZRSR2 ZRSR2P1	3 interacting genes: REP15 SRRM4 U2AF2
Entrez ID		11338	7310
HPRD ID		01872	03049
Ensembl ID		ENSG00000063244	ENSG00000212643
Uniprot IDs		P26368
PDB IDs		1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW 4TU7 4TU8 4TU9 5EV1 5EV2 5EV3 5EV4 5W0G 5W0H 6TR0 6XLV 6XLW 6XLX 7S3A 7S3B 7S3C 7SN6 8P25 9C7A 9C7B 9DWU
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Binding RNA Metabolic Process Nucleic Acid Binding Nucleoplasm Regulation Of RNA Splicing Nucleic Acid Metabolic Process Nucleus Spliceosomal Complex Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nuclear Speck Regulation Of Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Binding Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process U2AF Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Positive Regulation Of Biosynthetic Process RS Domain Binding Pre-mRNA 3'-splice Site Binding Protein-containing Complex Assembly U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex MRNA Splice Site Recognition Negative Regulation Of RNA Metabolic Process Protein-containing Complex Organization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Splicing	Regulation Of RNA Splicing Regulation Of MRNA Processing Poly-pyrimidine Tract Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Commitment Complex U2AF Complex Pre-mRNA 3'-splice Site Binding RNA Splicing MRNA Processing Transferrin Transport Prp19 Complex C2H2 Zinc Finger Domain Binding U2-type Prespliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of RNA Splicing Receptor Recycling Neuron Maturation Molecular Function Inhibitor Activity Positive Regulation Of RNA Splicing Spliceosomal Complex Assembly RNA Processing Iron Ion Transport Receptor Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?