U2AF2 and ZRSR2

Number of citations of the paper that reports this interaction (PMID 9237760)
34

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		U2AF2	ZRSR2
Gene Name		U2 small nuclear RNA auxiliary factor 2	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Prp19 Complex Nucleoplasm Spliceosomal Complex Nuclear Speck	U12-type Spliceosomal Complex
	Molecular Function	Nucleotide Binding Protein Binding Enzyme Binding Poly(A) RNA Binding C2H2 Zinc Finger Domain Binding	Nucleotide Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		51 interactors: AES APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX17 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA HNRNPA0 HNRNPD HNRNPK IL7R KHDRBS1 KHDRBS3 KIAA0907 LURAP1 MAP1B PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TOP1 U2AF1 WT1 ZRSR2	10 interactors: APP CLK2 SDCBP2 SRPK1 SRPK2 SRSF1 SRSF2 SSX2IP U2AF1 U2AF2
Entrez ID		11338	8233
HPRD ID		01872	02068
Ensembl ID		ENSG00000063244	ENSG00000169249
Uniprot IDs		P26368	Q15696
PDB IDs		1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Biosynthetic Process Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Stability Regulation Of RNA Stability Cellular Process DNA-templated Transcription, Termination Regulation Of Translation MRNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Female Gonad Development Circadian Regulation Of Translation RNA 3'-end Processing	MRNA Processing MRNA 3'-end Processing Regulation Of RNA Splicing MRNA Metabolic Process RNA 3'-end Processing RNA Processing Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Intracellular Transport Nucleocytoplasmic Transport Establishment Of Localization In Cell Nuclear Transport Cellular Localization Positive Regulation Of Viral Genome Replication RNA Metabolic Process Gene Expression Cytoplasmic Transport Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Transcription From RNA Polymerase II Promoter Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transport Nucleus Organization Cellular Nitrogen Compound Metabolic Process Collateral Sprouting In Absence Of Injury Microtubule-based Transport Protein Phosphorylation Cytoskeleton-dependent Intracellular Transport Regulation Of Viral Process Collateral Sprouting
Tagcloud ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine	bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1
Tagcloud (Difference) ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice u2af1 uridine	bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase subclonal unfavourable warranted wt1
Tagcloud (Intersection) ?		splicing