USP18 and ZDHHC17

Number of citations of the paper that reports this interaction (PMID 24705354)
0

Data Source:
BioGRID (two hybrid)

		USP18	ZDHHC17
Gene Name		ubiquitin specific peptidase 18	zinc finger, DHHC-type containing 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Golgi Membrane Cytoplasm Golgi Apparatus Integral Component Of Membrane Golgi-associated Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding ISG15-specific Protease Activity	Signal Transducer Activity Protein Binding Zinc Ion Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding
	Biological Process	Protein Deubiquitination Cytokine-mediated Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process	Signal Transduction Magnesium Ion Transport Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Regulation of IFNA signaling ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: IFNAR2 ISG15 TRIM54 ZDHHC17	191 interactors: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM122C FAM135B FAM207A FAM9A FBXO18 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 HBG1 HECTD3 HIST1H2BH HIST1H3H HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT HYPM IFT20 IFT57 INPP5D JMJD7-PLA2G4B KIAA0141 KIAA0226L KIAA0408 KIAA0907 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LOC401296 LOC554206 LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF OBFC1 ODF2 OFCC1 OTUD7B OTX2 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY4 SREBF2 SRSF4 STK25 SUMF2 SYT1 TAF8 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZCCHC6 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		11274	23390
HPRD ID		06136	09697
Ensembl ID		ENSG00000184979	ENSG00000186908
Uniprot IDs		Q53Y90 Q9UMW8	Q8IUH5
PDB IDs			3EU9
Enriched GO Terms of Interacting Partners?		Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Response To Virus ISG15-protein Conjugation Cytokine-mediated Signaling Pathway Signal Transduction Response To Interferon-alpha Signaling Lipoprotein Transport Positive Regulation Of Erythrocyte Differentiation Magnesium Ion Transport Cellular Response To Cytokine Stimulus Cell Communication Protein Palmitoylation Response To Cytokine Response To Other Organism Response To Biotic Stimulus Negative Regulation Of Microtubule Depolymerization Regulation Of Erythrocyte Differentiation Cellular Response To Stimulus Innate Immune Response Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Type I Interferon Production Negative Regulation Of Viral Genome Replication Negative Regulation Of Microtubule Polymerization Or Depolymerization JAK-STAT Cascade	Regulation Of Metabolic Process Transcription, DNA-templated RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Cellular Process Organelle Organization Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Neurotransmitter Uptake Developmental Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Golgi Organization Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Transcription, DNA-templated Chromatin Organization Cellular Component Assembly Regulation Of Gene Silencing Gene Silencing RNA 3'-end Processing Embryo Development Visual Learning Regulation Of Cell Projection Organization Visual Behavior RNA Processing
Tagcloud ?		appearance downregulating egress exploits g3bp1 granule granules hairpin hcv illustrate infectious infectivity interferon inverse machinery mxa opting rasgap sg sgs sh3 shrna tia tia1 tiar titers triggering triggers ways	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 il6st jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Difference) ?		appearance downregulating egress exploits g3bp1 granule granules hairpin hcv illustrate infectious infectivity interferon inverse machinery mxa opting rasgap sg sgs sh3 shrna tia tia1 tiar titers triggering triggers ways	1b atr atxn3 bcl11b cdkn1a cep290 cxcl5 dmxl1 ensured gfi gnal gnl3l gpr65 gtf2h3 il6st jem knocked lamp1 megakaryocytic mycbp pld1 rac3 rbbp6 reserve rigorous smc3 tmem30 tpr znf292
Tagcloud (Intersection) ?