USP18

Gene Name		ubiquitin specific peptidase 18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding ISG15-specific Protease Activity
	Biological Process	Protein Deubiquitination Cytokine-mediated Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process
Pathways		Regulation of IFNA signaling ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: IFNAR2 ISG15 TRIM54 ZDHHC17
Entrez ID		11274
HPRD ID		06136
Ensembl ID		ENSG00000184979
Uniprot IDs		Q53Y90 Q9UMW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Response To Virus ISG15-protein Conjugation Cytokine-mediated Signaling Pathway Signal Transduction Response To Interferon-alpha Signaling Lipoprotein Transport Positive Regulation Of Erythrocyte Differentiation Magnesium Ion Transport Cellular Response To Cytokine Stimulus Cell Communication Protein Palmitoylation Response To Cytokine Response To Other Organism Response To Biotic Stimulus Negative Regulation Of Microtubule Depolymerization Regulation Of Erythrocyte Differentiation Cellular Response To Stimulus Innate Immune Response Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Type I Interferon Production Negative Regulation Of Viral Genome Replication Negative Regulation Of Microtubule Polymerization Or Depolymerization JAK-STAT Cascade
Tagcloud ?		appearance downregulating egress exploits g3bp1 granule granules hairpin hcv illustrate infectious infectivity interferon inverse machinery mxa opting rasgap sg sgs sh3 shrna tia tia1 tiar titers triggering triggers ways