SNF8 and SUV39H2

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SNF8	SUV39H2
Gene Name		SNF8, ESCRT-II complex subunit	suppressor of variegation 3-9 homolog 2 (Drosophila)
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Gene Ontology Annotations	Cellular Component	ESCRT II Complex Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Late Endosome Membrane Extracellular Vesicular Exosome	Chromosome, Centromeric Region Chromatin Nucleoplasm Nuclear Heterochromatin
	Molecular Function	Protein Binding Transcription Factor Binding Protein Homodimerization Activity	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific)
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Endosomal Transport Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Positive Regulation Of Exosomal Secretion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Assembly Or Disassembly Chromatin Remodeling Transcription, DNA-templated Male Meiosis Cell Differentiation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT)	Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990)
Protein-Protein Interactions		15 interactors: ADORA1 CHMP6 DVL2 ELL GOLGA2 KDM1A NIF3L1 PRMT6 RILP SUV39H2 TRIM54 TSG101 VAC14 VPS25 VPS36	39 interactors: AKAP9 APPL2 BLZF1 C8orf74 CBX5 CBX7 CCDC151 CCDC37 CDCA4 CEP70 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		11267	79723
HPRD ID		16847	07580
Ensembl ID			ENSG00000152455
Uniprot IDs		Q96H20	Q9H5I1
PDB IDs		2ZME 3CUQ	2R3A
Enriched GO Terms of Interacting Partners?		Endosomal Transport Vacuolar Transport Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Circadian Rhythm Protein Localization Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Protein Transport Regulation Of Gene Expression Regulation Of Metabolic Process Establishment Of Protein Localization Intracellular Transport Transcription, DNA-templated Positive Regulation Of Protein Tyrosine Kinase Activity RNA Biosynthetic Process Cellular Localization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Negative Regulation Of Long Term Synaptic Depression Negative Regulation Of Neurotrophin Production Positive Regulation Of Nucleoside Transport Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Regulation Of Protein Tyrosine Kinase Activity Biosynthetic Process Establishment Of Localization In Cell Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Histone H3-R2 Methylation Negative Regulation Of Mucus Secretion 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Negative Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Circadian Rhythm Histone Modification Negative Regulation Of Binding RNA Metabolic Process Convergent Extension Involved In Neural Plate Elongation Regulation Of Long Term Synaptic Depression Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K27 Methylation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Osteoblast Differentiation Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Golgi To Plasma Membrane Transport Positive Regulation Of Histone Methylation Nitrogen Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Osteoclast Maturation Regulation Of Histone Methylation Regulation Of Ossification Protein Targeting Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Membrane Positive Regulation Of DNA Replication Positive Regulation Of Histone Modification Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Osteoblast Differentiation Myeloid Cell Differentiation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization To Plasma Membrane Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
Tagcloud ?		cerevisiae cloning complementation dalton derepression diploids distinguished extremely homozygous impair invertase limitation notably predicts raffinose saccharomyces sick snf1 snf2 snf4 snf5 snf6 snf7 sporulation spt6 ssn20 ssn6 suc2 suppressors	a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Difference) ?		cerevisiae cloning complementation dalton derepression diploids distinguished extremely homozygous impair invertase limitation notably predicts raffinose saccharomyces sick snf1 snf2 snf4 snf5 snf6 snf7 sporulation spt6 ssn20 ssn6 suc2 suppressors	a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Intersection) ?