CHML and RABGGTB

Number of citations of the paper that reports this interaction (PubMedID 12535645)
0

Data Source:
HPRD (in vitro)

		CHML	RABGGTB
Description		CHM like Rab escort protein	Rab geranylgeranyltransferase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Cytoplasm Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GDP-dissociation Inhibitor Activity GTPase Activator Activity Small GTPase Binding	Catalytic Activity Prenyltransferase Activity Protein Geranylgeranyltransferase Activity Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Protein Prenyltransferase Activity Transferase Activity Small GTPase Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Small GTPase-mediated Signal Transduction Vesicle-mediated Transport Protein Geranylgeranylation	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Visual Perception Protein Geranylgeranylation Protein Modification Process
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs			N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		5 interacting genes: RAB1A RAB3A RAB5A RAB6A RABGGTB	19 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A SH3GLB1 TAFA1 TMEM25 WDR4
Entrez ID		1122	5876
HPRD ID		00341	01532
Ensembl ID		ENSG00000203668	ENSG00000137955
Uniprot IDs		P26374	A8KAJ2 P53611 Q6IB63
PDB IDs			6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Vesicle-mediated Transport Myosin V Binding Synaptic Vesicle Recycling Establishment Of Localization In Cell Endomembrane System Establishment Of Organelle Localization Golgi Vesicle Transport Terminal Bouton Regulation Of Synaptic Vesicle Exocytosis Regulation Of Neuronal Synaptic Plasticity Peptide Hormone Secretion Organelle Localization Protein Transport Intracellular Transport Organelle Transport Along Microtubule Peptide Secretion G Protein Activity Regulation Of Presynaptic Dense Core Granule Exocytosis Regulation Of Neurotransmitter Secretion Positive Regulation Of Exocytosis Evoked Neurotransmitter Secretion Peptidyl-cysteine Methylation Establishment Of Protein Localization Hormone Secretion Peptide Transport Secretory Granule Membrane Hormone Transport Melanosome Intracellular Protein Transport Establishment Of Vesicle Localization Sensory Perception Of Touch Vesicle Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Regulated Secretory Pathway Synaptic Vesicle Synaptic Vesicle Membrane Amide Transport Hydrolase Activity Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Protein Localization To Early Endosome Endosome To Plasma Membrane Transport Vesicle Nucleotide Binding Intracellular Protein Localization Signal Release Clathrin-sculpted Glutamate Transport Vesicle Membrane Cytoplasmic Side Of Early Endosome Membrane	G Protein Activity GTPase Activity Myosin V Binding GTP Binding Endosome Establishment Of Vesicle Localization Vesicle Localization Establishment Of Organelle Localization Synaptic Vesicle Recycling Protein Transport Establishment Of Melanosome Localization Melanosome Localization Melanosome Transport Pigment Granule Transport Regulation Of Exocytosis Positive Regulation Of Exocytosis Pigment Granule Localization Establishment Of Protein Localization Nucleotide Binding Exosomal Secretion Intracellular Protein Localization Organelle Localization Synaptic Vesicle Membrane Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Amyloid-beta Clearance By Transcytosis Cytoplasmic Vesicle Hydrolase Activity Presynaptic Endosome Regulation Of Neuronal Synaptic Plasticity Regulation Of Secretion Plasma Membrane To Endosome Transport Golgi Apparatus GDP Binding Endosome To Plasma Membrane Protein Transport Phagocytic Vesicle Neurotransmitter Receptor Transport Regulation Of Plasma Membrane Organization Vesicle-mediated Transport In Synapse Establishment Of Localization In Cell Secretory Granule Membrane Endosomal Transport Melanosome Transcytosis Melanosome Membrane Positive Regulation Of Secretion By Cell Early Endosome To Late Endosome Transport Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway
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