DHX9 and STAU1

Number of citations of the paper that reports this interaction (PMID 15121898)
40

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		DHX9	STAU1
Gene Name		DEAH (Asp-Glu-Ala-His) box helicase 9	staufen double-stranded RNA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule CRD-mediated MRNA Stability Complex	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Microtubule Associated Complex Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding RNA Helicase Activity ATP-dependent DNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing Circadian Rhythm RNA Splicing Gene Expression Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Cellular Response To Heat Innate Immune Response CRD-mediated MRNA Stabilization	Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Pathways		mRNA Splicing Toll Like Receptor 7/8 (TLR7/8) Cascade Toll Like Receptor TLR6:TLR2 Cascade RIP-mediated NFkB activation via ZBP1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Toll Like Receptor TLR1:TLR2 Cascade Activated TLR4 signalling MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade ZBP1(DAI) mediated induction of type I IFNs MyD88 dependent cascade initiated on endosome MyD88:Mal cascade initiated on plasma membrane TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Toll Like Receptor 9 (TLR9) Cascade Innate Immune System Processing of Capped Intron-Containing Pre-mRNA TRIF-mediated TLR3/TLR4 signaling Cytosolic sensors of pathogen-associated DNA mRNA Splicing - Major Pathway MyD88-independent cascade Toll Like Receptor 2 (TLR2) Cascade RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor 3 (TLR3) Cascade TRAF6 mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: ACTA1 AKAP8L APBB1 BRCA1 DDX20 DDX5 EIF2AK2 EWSR1 GEMIN2 GEMIN4 GTF2B H2AFX HDLBP HNRNPC HNRNPK IL7R ILF3 JUN KHDRBS1 MBD2 MGEA5 NXF1 PCNA POLR2A PRMT1 PRPF40A PRPF8 RBM4 RELA SMN1 SMN2 SNRPB SNRPB2 SRPK1 SSRP1 STAU1 TBP TOP2A UBE2I YWHAQ	39 interactors: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TUBB TUBB4A UBE2D3 UPF1 ZMAT3
Entrez ID		1660	6780
HPRD ID		04386	03422
Ensembl ID		ENSG00000135829	ENSG00000124214
Uniprot IDs		B3KU66 Q08211	B3KRE0 O95793 Q6PJX3
PDB IDs		3LLM 3VYX 3VYY	4DKK
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Regulation Of Viral Process Regulation Of Viral Genome Replication Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Viral Process Positive Regulation Of DNA Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Viral Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecular Complex Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Negative Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Metabolic Process RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Chromosome Organization Positive Regulation Of Response To DNA Damage Stimulus Negative Regulation Of Viral Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Genome Replication	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Intracellular Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Localization RNA Transport Cytoskeleton-dependent Intracellular Transport RNA Localization Viral Process Establishment Of Localization In Cell MRNA Processing Viral Transcription SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Protein Complex Disassembly Cotranslational Protein Targeting To Membrane Protein Targeting To ER Viral Life Cycle Neuron Projection Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Catabolic Process Protein Complex Disassembly RNA Splicing Cytoplasmic Transport MRNA Transport Axonogenesis Organelle Transport Along Microtubule Protein Localization To Endoplasmic Reticulum Translational Initiation Microtubule-based Transport Movement Of Cell Or Subcellular Component Microtubule-based Process Axon Development RNA Processing Translational Termination Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of Translation Cell Projection Morphogenesis Protein Targeting To Membrane RNA Export From Nucleus Cell Part Morphogenesis Translational Elongation MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Microtubule-based Movement Developmental Cell Growth
Tagcloud ?			activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Difference) ?			activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Intersection) ?