RAB6A and CHML

Number of citations of the paper that reports this interaction (PubMedID 8294464)
0

Data Source:
HPRD (in vitro)

		RAB6A	CHML
Description		RAB6A, member RAS oncogene family	CHM like Rab escort protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Nucleus Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding	GDP-dissociation Inhibitor Activity GTPase Activator Activity Small GTPase Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane	Intracellular Protein Transport Small GTPase-mediated Signal Transduction Vesicle-mediated Transport Protein Geranylgeranylation
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		23 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TIAM1 TMEM132D TMF1	5 interacting genes: RAB1A RAB3A RAB5A RAB6A RABGGTB
Entrez ID		5870	1122
HPRD ID		01543	00341
Ensembl ID		ENSG00000175582	ENSG00000203668
Uniprot IDs		A0A024R5J5 P20340 Q53ET8	P26374
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome	GTPase Activity GTP Binding Vesicle-mediated Transport Myosin V Binding Synaptic Vesicle Recycling Establishment Of Localization In Cell Endomembrane System Establishment Of Organelle Localization Golgi Vesicle Transport Terminal Bouton Regulation Of Synaptic Vesicle Exocytosis Regulation Of Neuronal Synaptic Plasticity Peptide Hormone Secretion Organelle Localization Protein Transport Intracellular Transport Organelle Transport Along Microtubule Peptide Secretion G Protein Activity Regulation Of Presynaptic Dense Core Granule Exocytosis Regulation Of Neurotransmitter Secretion Positive Regulation Of Exocytosis Evoked Neurotransmitter Secretion Peptidyl-cysteine Methylation Establishment Of Protein Localization Hormone Secretion Peptide Transport Secretory Granule Membrane Hormone Transport Melanosome Intracellular Protein Transport Establishment Of Vesicle Localization Sensory Perception Of Touch Vesicle Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Regulated Secretory Pathway Synaptic Vesicle Synaptic Vesicle Membrane Amide Transport Hydrolase Activity Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Protein Localization To Early Endosome Endosome To Plasma Membrane Transport Vesicle Nucleotide Binding Intracellular Protein Localization Signal Release Clathrin-sculpted Glutamate Transport Vesicle Membrane Cytoplasmic Side Of Early Endosome Membrane
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