RAB6A and CHML

Number of citations of the paper that reports this interaction (PMID 8294464)
30

Data Source:
HPRD (in vitro)

		RAB6A	CHML
Gene Name		RAB6A, member RAS oncogene family	choroideremia-like (Rab escort protein 2)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Rab Geranylgeranyltransferase Activity GTPase Activator Activity Rab GTPase Binding
	Biological Process	Protein Targeting To Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule	Intracellular Protein Transport Protein Geranylgeranylation Positive Regulation Of GTPase Activity
Pathways		Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1	5 interactors: RAB1A RAB3A RAB5A RAB6A RABGGTB
Entrez ID		5870	1122
HPRD ID		01543	00341
Ensembl ID		ENSG00000175582	ENSG00000203668
Uniprot IDs		P20340 Q53ET8	P26374
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX
Enriched GO Terms of Interacting Partners?		Protein Geranylgeranylation Protein Localization Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Prenylation Protein Transport Establishment Of Protein Localization Minus-end-directed Organelle Transport Along Microtubule Cellular Protein Localization Transport Retrograde Transport, Endosome To Golgi Microtubule Anchoring At Microtubule Organizing Center Intracellular Protein Transport Vesicle-mediated Transport Microtubule-based Movement Positive Regulation Of Hydrolase Activity Microtubule-based Transport Protein Targeting To Golgi Cytoskeleton-dependent Intracellular Transport Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Protein Targeting Organelle Assembly Protein Localization To Golgi Apparatus Endosomal Transport Protein Localization To Organelle Regulation Of Proteinase Activated Receptor Activity Epidermal Growth Factor Catabolic Process Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Testosterone Secretion Positive Regulation Of Catalytic Activity Organelle Transport Along Microtubule Intra-Golgi Vesicle-mediated Transport Microtubule Anchoring Rab Protein Signal Transduction Regulation Of Catalytic Activity Luteinizing Hormone Secretion Negative Regulation Of Phospholipase C Activity Positive Regulation Of Androgen Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Establishment Of Protein Localization To Organelle Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phagosome-lysosome Fusion Phagosome Acidification Negative Regulation Of Protein Targeting To Membrane	Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Establishment Of Vesicle Localization Vesicle Localization Intracellular Protein Transport Regulation Of Synaptic Vesicle Exocytosis Synaptic Vesicle Recycling Establishment Of Organelle Localization Regulation Of Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Neuronal Synaptic Plasticity Organelle Transport Along Microtubule Organelle Localization Protein Transport Positive Regulation Of Exocytosis Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Neurotransmitter Secretion Intracellular Transport Intracellular Signal Transduction Endocytosis Protein Localization Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Cytoplasmic Transport Establishment Of Localization In Cell Protein Secretion Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Regulation Of Exocytosis Regulation Of Synaptic Plasticity Cellular Localization Cell-cell Signaling Peptidyl-cysteine Methylation Constitutive Secretory Pathway Regulation Of Endosome Size Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Sensory Perception Of Touch Receptor Internalization Involved In Canonical Wnt Signaling Pathway Minus-end-directed Organelle Transport Along Microtubule Endosomal Transport Vesicle Organization Interleukin-8 Production Golgi Vesicle Transport Protein Geranylgeranylation Regulation Of Synaptic Transmission Microtubule-based Movement
Tagcloud ?		autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Difference) ?		autosomal axonal causal coh1 cohen constitutively disability dystrophy golgi gtpase inactive integrity intellectual interfered microcephaly neurite neuritogenesis outgrowth preferentially preparations prevents q72l recessive rnai scaffold solubilization t27n vps13b
Tagcloud (Intersection) ?