RAB6A and TMF1

Number of citations of the paper that reports this interaction (PubMedID 15128430)
21

Data Source:
HPRD (in vitro)

		RAB6A	TMF1
Description		RAB6A, member RAS oncogene family	TATA element modulatory factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding	DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Androgen Receptor Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane	Acrosome Assembly Positive Regulation Of Cytokine Production Apoptotic Process Spermatid Development Spermatid Nucleus Differentiation Male Gonad Development Negative Regulation Of Gene Expression Flagellated Sperm Motility Androgen Receptor Signaling Pathway Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Epithelial Cell Apoptotic Process Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Testosterone Secretion
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Meat-related diet ( 32066663) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TIAM1 TMEM132D TMF1	9 interacting genes: AR CMTM5 FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4
Entrez ID		5870	7110
HPRD ID		01543	03081
Ensembl ID		ENSG00000175582	ENSG00000144747
Uniprot IDs		A0A024R5J5 P20340 Q53ET8	P82094 Q6PII6
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome	Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Estrogen Response Element Binding Protein-containing Complex Seminiferous Tubule Development Negative Regulation Of Transcription By RNA Polymerase II Steroid Binding Chromatin Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Gluconeogenesis Positive Regulation Of Gene Expression, Epigenetic Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Prostate Induction Lipid Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Cellular Response To Oxygen-containing Compound RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Male Somatic Sex Determination Cellular Response To Hormone Stimulus Regulation Of Developmental Process Adherens Junction Disassembly Nuclear Glucocorticoid Receptor Activity Chromatin Organization Peptidyl-cysteine Methylation Regulation Of Myoblast Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cellular Response To Steroid Hormone Stimulus Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Cell-cell Junction Disassembly Negative Regulation Of RRNA Processing Histone H3K9 Acetyltransferase Activity Clathrin-dependent Synaptic Vesicle Endocytosis DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Regulation Of Glucose Metabolic Process Nuclear Receptor-mediated Signaling Pathway Male Gonad Development Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Integrin Biosynthetic Process
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