RAB6A and PMM1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		RAB6A	PMM1
Description		RAB6A, member RAS oncogene family	phosphomannomutase 1
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GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Ciliary Basal Body Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Myosin V Binding	Phosphomannomutase Activity Protein Binding Isomerase Activity Metal Ion Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Neuron Projection Development Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule Protein Localization To Golgi Membrane	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Nucleoside Phosphate Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		23 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TIAM1 TMEM132D TMF1	5 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RCHY1
Entrez ID		5870	5372
HPRD ID		01543	03473
Ensembl ID		ENSG00000175582	ENSG00000100417
Uniprot IDs		A0A024R5J5 P20340 Q53ET8	Q92871
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF	2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Golgi Apparatus Vesicle-mediated Transport Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Cellular Localization Intracellular Transport Protein Prenylation Microtubule Anchoring At Microtubule Organizing Center Protein Transport GDP-dissociation Inhibitor Activity Establishment Of Localization In Cell Establishment Of Protein Localization Microtubule Anchoring Intracellular Protein Localization Minus-end-directed Organelle Transport Along Microtubule Rab Geranylgeranyltransferase Activity GTPase Activator Activity Golgi Vesicle Transport Organelle Assembly Cytosol Trans-Golgi Network Cytoplasm Positive Regulation Of Axonogenesis Microtubule-based Movement Dynactin Binding Microtubule Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Dynein Complex Binding Retromer Complex Cytoskeletal Anchor Activity Small GTPase-mediated Signal Transduction Establishment Of Organelle Localization Microtubule-based Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytosolic Transport Maintenance Of Synapse Structure Vesicle-mediated Transport To The Plasma Membrane Cytoplasmic Vesicle Mitotic Spindle Regulation Of Axonogenesis Microtubule Associated Complex Positive Regulation Of Axon Extension GTPase Binding Synaptic Vesicle Recycling Via Endosome Neuronal Cell Body Regulation Of Microtubule Cytoskeleton Organization Golgi Membrane Transport Along Microtubule Centrosome	Protein Localization To Golgi Membrane Myosin V Binding Protein Localization To Golgi Apparatus Intra-Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum GTP Binding Peptidyl-cysteine Methylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cytosolic Transport Retrograde Transport, Endosome To Golgi Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Post-translational Protein Modification Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process VCB Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Minus-end-directed Organelle Transport Along Microtubule NEDD8 Ligase Activity Cul7-RING Ubiquitin Ligase Complex Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Base-excision Repair, AP Site Formation Via Deaminated Base Removal NEDD8 Transferase Activity Error-free Translesion Synthesis Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Autoubiquitination Regulation Of Protein Ubiquitination Cul4B-RING E3 Ubiquitin Ligase Complex Positive Regulation Of Protein Catabolic Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Post-translational Protein Modification Negative Regulation Of Response To Oxidative Stress Ubiquitin-protein Transferase Activity Endosomal Transport Endomembrane System Golgi Vesicle Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Negative Regulation Of Mitophagy Transcription-coupled Nucleotide-excision Repair High Voltage-gated Calcium Channel Activity Protein Localization To Membrane Ubiquitin Protein Ligase Binding GTPase Activity Ciliary Basal Body Cul4A-RING E3 Ubiquitin Ligase Complex Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
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