MAP1B and STRAP

Number of citations of the paper that reports this interaction (PubMedID 16014633)
0

Data Source:
HPRD (in vitro, in vivo)

		MAP1B	STRAP
Description		microtubule associated protein 1B	serine/threonine kinase receptor associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Axon Dendrite Growth Cone Somatodendritic Compartment Cell Projection Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber Postsynapse Glutamatergic Synapse	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Protein-containing Complex Binding	RNA Binding MRNA Binding Signaling Receptor Binding Protein Binding U2 SnRNP Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Nervous System Development Axonogenesis Synapse Assembly Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Carbohydrate Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Neuron Projection Development Response To Nutrient Levels Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Intracellular Transport Mitochondrion Transport Along Microtubule Neuron Development Axon Extension Response To Axon Injury Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Odontoblast Differentiation Regulation Of Postsynapse Assembly	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Protein-RNA Complex Assembly Neuron Differentiation Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways		RSV-host interactions	Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling Positive Regulation of CDH1 Gene Transcription
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241) Refractive error ( 32231278)
Interacting Genes		36 interacting genes: ACTB ANP32A ARHGEF11 CREBBP CSNK2A1 DYNLL1 EEF1D ERBB3 FOS GABRR1 GABRR2 GAN GSK3B HMGB1 HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NEIL3 NXF1 NXF2 PAFAH1B1 PRKAR1A RASSF1 RNF10 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2 VHL	31 interacting genes: ANXA1 CEBPA CHEK2 FOXP1 GEMIN6 GEMIN7 MAP1B MTRES1 NEIL3 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2
Entrez ID		4131	11171
HPRD ID		01139	05816
Ensembl ID		ENSG00000131711	ENSG00000023734
Uniprot IDs		A2BDK6 P46821 Q6PJD3 Q86X89	Q9Y3F4
PDB IDs
Enriched GO Terms of Interacting Partners?		Tau Protein Binding Positive Regulation Of Cell Communication Cellular Response To Stress Positive Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signaling Microtubule Associated Complex Axon Regulation Of Norepinephrine Uptake Regulation Of Biological Quality JNK Cascade Intracellular Signaling Cassette Intracellular Signal Transduction Transporter Regulator Activity Regulation Of Autophagy Regulation Of Cellular Response To Stress Regulation Of Protein Localization Negative Regulation Of Gene Expression Synapse Glutamatergic Synapse Positive Regulation Of Macromolecule Metabolic Process Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Protein Localization Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Cell Development Chemical Synaptic Transmission Positive Regulation Of Biosynthetic Process Regulation Of Postsynaptic Membrane Potential Pre-mRNA 3'-splice Site Binding U2AF Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Cellular Response To Oxidative Stress Trans-synaptic Signaling Synaptic Signaling Modulation Of Chemical Synaptic Transmission Nuclear RNA Export Factor Complex Negative Regulation Of Macromolecule Biosynthetic Process Response To Stress Substantia Nigra Development Regulation Of Apoptotic Process Nitric-oxide Synthase Regulator Activity Positive Regulation Of Macromolecule Biosynthetic Process	SMN-Sm Protein Complex I-SMAD Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Heteromeric SMAD Protein Complex 7-methylguanosine Cap Hypermethylation SMAD Protein Signal Transduction U2 SnRNP Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein-RNA Complex Assembly Type I Transforming Growth Factor Beta Receptor Binding U4 SnRNP Response To Growth Factor Methylosome Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Small Nuclear Ribonucleoprotein Complex Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway U1 SnRNP Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway U5 SnRNP Regulation Of Epithelial To Mesenchymal Transition RNA Splicing, Via Transesterification Reactions Activin Receptor Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex Nucleoplasm R-SMAD Binding Regulation Of SMAD Protein Signal Transduction Trophoblast Cell Migration U7 SnRNP U2-type Spliceosomal Complex Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Ureteric Bud Development SMN Complex Ubiquitin Protein Ligase Binding Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Ossification Co-SMAD Binding Gemini Of Cajal Bodies Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splicing, Via Spliceosome Mesonephric Tubule Development Mesonephric Epithelium Development SMAD Binding
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