MAP1B and MAG

Number of citations of the paper that reports this interaction (PubMedID 11733546)
28

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		MAP1B	MAG
Description		microtubule associated protein 1B	myelin associated glycoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Axon Dendrite Growth Cone Somatodendritic Compartment Cell Projection Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber Postsynapse Glutamatergic Synapse	Plasma Membrane Membrane Paranode Region Of Axon Myelin Sheath Adaxonal Region Myelin Sheath Compact Myelin Schmidt-Lanterman Incisure Membrane Raft Mesaxon
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Protein-containing Complex Binding	Signaling Receptor Binding Lipid Binding Protein Kinase Binding Carbohydrate Binding Sialic Acid Binding Protein Homodimerization Activity Ganglioside GT1b Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Nervous System Development Axonogenesis Synapse Assembly Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Carbohydrate Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Neuron Projection Development Response To Nutrient Levels Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Intracellular Transport Mitochondrion Transport Along Microtubule Neuron Development Axon Extension Response To Axon Injury Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Odontoblast Differentiation Regulation Of Postsynapse Assembly	Cell Adhesion Nervous System Development Negative Regulation Of Neuron Projection Development Transmission Of Nerve Impulse Substantia Nigra Development Central Nervous System Myelination Negative Regulation Of Axon Extension Axon Regeneration Positive Regulation Of Myelination Central Nervous System Myelin Formation Myelination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Cellular Response To Mechanical Stimulus Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		RSV-host interactions	Axonal growth inhibition (RHOA activation) Basigin interactions EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241) Refractive error ( 32231278)
Interacting Genes		36 interacting genes: ACTB ANP32A ARHGEF11 CREBBP CSNK2A1 DYNLL1 EEF1D ERBB3 FOS GABRR1 GABRR2 GAN GSK3B HMGB1 HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NEIL3 NXF1 NXF2 PAFAH1B1 PRKAR1A RASSF1 RNF10 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2 VHL	18 interacting genes: APP COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL6A1 COL9A1 COL9A2 COL9A3 FN1 FYN MAP1B MBP NGFR PLP1 PRNP RTN4R
Entrez ID		4131	4099
HPRD ID		01139	01160
Ensembl ID		ENSG00000131711	ENSG00000105695
Uniprot IDs		A2BDK6 P46821 Q6PJD3 Q86X89	P20916 Q53ES7
PDB IDs
Enriched GO Terms of Interacting Partners?		Tau Protein Binding Positive Regulation Of Cell Communication Cellular Response To Stress Positive Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signaling Microtubule Associated Complex Axon Regulation Of Norepinephrine Uptake Regulation Of Biological Quality JNK Cascade Intracellular Signaling Cassette Intracellular Signal Transduction Transporter Regulator Activity Regulation Of Autophagy Regulation Of Cellular Response To Stress Regulation Of Protein Localization Negative Regulation Of Gene Expression Synapse Glutamatergic Synapse Positive Regulation Of Macromolecule Metabolic Process Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Protein Localization Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Cell Development Chemical Synaptic Transmission Positive Regulation Of Biosynthetic Process Regulation Of Postsynaptic Membrane Potential Pre-mRNA 3'-splice Site Binding U2AF Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Cellular Response To Oxidative Stress Trans-synaptic Signaling Synaptic Signaling Modulation Of Chemical Synaptic Transmission Nuclear RNA Export Factor Complex Negative Regulation Of Macromolecule Biosynthetic Process Response To Stress Substantia Nigra Development Regulation Of Apoptotic Process Nitric-oxide Synthase Regulator Activity Positive Regulation Of Macromolecule Biosynthetic Process	Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Platelet-derived Growth Factor Binding Endoplasmic Reticulum Lumen Extracellular Matrix Fibrillar Collagen Trimer Basement Membrane Collagen Type IX Trimer Extracellular Matrix Structural Constituent Anatomical Structure Morphogenesis Skin Development Extracellular Matrix Organization Extracellular Structure Organization Collagen Fibril Organization System Development Cellular Response To Amino Acid Stimulus Protease Binding Extracellular Region Response To Amino Acid Cellular Response To Amyloid-beta Regulation Of Dendritic Spine Maintenance Developmental Process Proteoglycan Binding Regulation Of Postsynapse Organization Perikaryon Response To Amyloid-beta Animal Organ Morphogenesis Response To Mechanical Stimulus Cartilage Development Basement Membrane Organization Type 5 Metabotropic Glutamate Receptor Binding Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Growth Factor Receptor Binding Response To Xenobiotic Stimulus Collagen Type XI Trimer Negative Regulation Of Dendritic Spine Maintenance Neuron Projection Organization Regulation Of Synapse Organization Growth Cone Integrin Binding Response To Growth Factor Blood Vessel Development Central Nervous System Development Sensory Perception Of Mechanical Stimulus Nervous System Process Heparin Binding Homeostatic Process Limb Joint Morphogenesis Cellular Developmental Process
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