MAP1B and GABRR2

Number of citations of the paper that reports this interaction (PMID 11102469)
7

Data Source:
HPRD (in vitro)

		MAP1B	GABRR2
Gene Name		microtubule-associated protein 1B	gamma-aminobutyric acid (GABA) A receptor, rho 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Cell Junction Dendritic Spine	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Domain Specific Binding
	Biological Process	Microtubule Bundle Formation Cellular Process Dendrite Development Negative Regulation Of Intracellular Transport Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Establishment Of Monopolar Cell Polarity	Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Visual Perception Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport
Pathways			GABA receptor activation GABA A (rho) receptor activation Ion channel transport Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		27 interactors: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D FOS GABRR1 GABRR2 GAN GSK3B LRRK2 MAG MAGOH MAP1A MAPK8 MARCH5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2	5 interactors: CSNK2A1 GABRR1 MAP1B PRKCA SQSTM1
Entrez ID		4131	2570
HPRD ID		01139	15922
Ensembl ID		ENSG00000131711	ENSG00000111886
Uniprot IDs		P46821 Q6PJD3 Q86X89	P28476
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Export MRNA Export From Nucleus RNA Localization Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Regulation Of Mitochondrion Organization MRNA Transport RNA Transport Positive Regulation Of Mitochondrion Organization Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cellular Component Organization Cellular Localization Negative Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cytoplasmic Transport Negative Regulation Of Neuron Projection Development Substantia Nigra Development Regulation Of Cell Morphogenesis Termination Of RNA Polymerase II Transcription Signaling Cell Communication Cellular Response To Inorganic Substance Negative Regulation Of Cell Projection Organization Regulation Of Neuron Maturation Response To Metal Ion Regulation Of Axonogenesis Negative Regulation Of Cell Development Neural Nucleus Development Negative Regulation Of Protein Binding Synaptic Transmission Positive Regulation Of Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Death Regulation Of Neuron Projection Development Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Immune System Process Cellular Response To Oxidative Stress DNA-templated Transcription, Termination Neurotrophin TRK Receptor Signaling Pathway Regulation Of Mitochondrial Fission MRNA 3'-end Processing Nervous System Development Neurotrophin Signaling Pathway Regulation Of Intracellular Transport MAPK Cascade	Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Cell Growth Histone H3-T6 Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Positive Regulation Of Growth Neurotrophin Signaling Pathway Positive Regulation Of Protein Metabolic Process Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Protein Phosphorylation Establishment Of Monopolar Cell Polarity Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Cell Differentiation Regulation Of Cell Growth Apoptotic Signaling Pathway Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Regulation Of Cell Death Mitochondrion Transport Along Microtubule Desmosome Organization Negative Regulation Of Transport Regulation Of Mitotic Cell Cycle Establishment Of Mitochondrion Localization Positive Regulation Of Macroautophagy Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Response To External Stimulus Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway Phosphorylation Negative Regulation Of Adenylate Cyclase Activity Axonogenesis Negative Regulation Of Lyase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Rhodopsin Mediated Signaling Pathway Axon Development Cellular Response To Growth Factor Stimulus
Tagcloud ?		accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Difference) ?		accelerated actin assembly barbed bundles cerevisiae coil coiled coisolated coronin coronins crn1delta crn1p cytoskeleton cytoskeletons dimerization filament filaments homologue linking links microtubule microtubules networks nucleation polymerization requirement saccharomyces stabilize
Tagcloud (Intersection) ?