RAB17 and MAGEA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RAB17	MAGEA1
Description		RAB17, member RAS oncogene family	MAGE family member A1
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Cytoplasmic Vesicle Dendrite Cytoplasm Melanosome Cell Projection Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Protein Transport Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly Cilium Assembly Anterograde Dendritic Transport Plasma Membrane Bounded Cell Projection Assembly	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		11 interacting genes: ACVR1 BOLA3 CSTPP1 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2 SNCA	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		64284	4100
HPRD ID		11468	02059
Ensembl ID		ENSG00000124839	ENSG00000198681
Uniprot IDs		Q9H0T7	P43355
PDB IDs			1W72 3BO8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Endocardial Cushion Cell Fate Commitment Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Cell Communication SMAD Binding Negative Regulation Of Signaling S100A8 Complex Positive Regulation Of Secretion Calprotectin Complex Neutrophil Aggregation Response To Desipramine Negative Regulation Of Serotonin Uptake Positive Regulation Of Exocytosis Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Transporter Regulator Activity Negative Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Regulation Of Norepinephrine Uptake Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Lipophagy Synaptic Vesicle Recycling Via Endosome 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Response To Lipoic Acid Establishment Of Vesicle Localization BMP Receptor Complex Peptidyl-cysteine S-nitrosylation Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Exosomal Secretion	TAP Binding Compartment Pattern Specification Protection From Natural Killer Cell Mediated Cytotoxicity MHC Class I Protein Complex Detection Of Bacterium Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Mitochondrial Fission Regulation Of Cellular Component Organization Response To External Biotic Stimulus Epidermal Cell Differentiation Negative Regulation Of Innate Immune Response Negative Regulation Of Myotube Differentiation Innate Immune Response Recycling Endosome Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Atrioventricular Valve Morphogenesis Endocardial Cushion Morphogenesis Positive Regulation Of Mitochondrial Fission Defense Response Host-mediated Perturbation Of Symbiont Process Notch Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Modulation Of Process Of Another Organism Defense Response To Other Organism Response To Other Organism Positive Regulation Of Epidermal Cell Differentiation Host-mediated Perturbation Of Viral Transcription Antigen Processing And Presentation Of Endogenous Antigen Regulation Of Mitochondrial Fission Lumenal Side Of Endoplasmic Reticulum Membrane Autophagy Detection Of Biotic Stimulus Positive Regulation Of Epidermis Development Endoderm Development Regulation Of Viral Process Positive Regulation Of Glial Cell Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Binding Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Venous Endothelial Cell Differentiation Coronary Sinus Valve Morphogenesis Foregut Morphogenesis Posterior Compartment Specification Anterior Compartment Pattern Formation S100A9 Complex Viral Process
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