RAB17

Description		RAB17, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Cytoplasmic Vesicle Dendrite Cytoplasm Melanosome Cell Projection Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Protein Transport Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly Cilium Assembly Anterograde Dendritic Transport Plasma Membrane Bounded Cell Projection Assembly
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		11 interacting genes: ACVR1 BOLA3 CSTPP1 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2 SNCA
Entrez ID		64284
HPRD ID		11468
Ensembl ID		ENSG00000124839
Uniprot IDs		Q9H0T7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Endocardial Cushion Cell Fate Commitment Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Cell Communication SMAD Binding Negative Regulation Of Signaling S100A8 Complex Positive Regulation Of Secretion Calprotectin Complex Neutrophil Aggregation Response To Desipramine Negative Regulation Of Serotonin Uptake Positive Regulation Of Exocytosis Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Transporter Regulator Activity Negative Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Regulation Of Norepinephrine Uptake Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Lipophagy Synaptic Vesicle Recycling Via Endosome 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Response To Lipoic Acid Establishment Of Vesicle Localization BMP Receptor Complex Peptidyl-cysteine S-nitrosylation Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Exosomal Secretion
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