RAB17 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10329441)
0

Data Source:
HPRD (two hybrid)

		RAB17	RABAC1
Description		RAB17, member RAS oncogene family	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Cytoplasmic Vesicle Dendrite Cytoplasm Melanosome Cell Projection Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Protein Transport Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly Cilium Assembly Anterograde Dendritic Transport Plasma Membrane Bounded Cell Projection Assembly
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		11 interacting genes: ACVR1 BOLA3 CSTPP1 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2 SNCA	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		64284	10567
HPRD ID		11468	05375
Ensembl ID		ENSG00000124839	ENSG00000105404
Uniprot IDs		Q9H0T7	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction Endocardial Cushion Cell Fate Commitment Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Cell Communication SMAD Binding Negative Regulation Of Signaling S100A8 Complex Positive Regulation Of Secretion Calprotectin Complex Neutrophil Aggregation Response To Desipramine Negative Regulation Of Serotonin Uptake Positive Regulation Of Exocytosis Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Transporter Regulator Activity Negative Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Regulation Of Norepinephrine Uptake Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Lipophagy Synaptic Vesicle Recycling Via Endosome 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Response To Lipoic Acid Establishment Of Vesicle Localization BMP Receptor Complex Peptidyl-cysteine S-nitrosylation Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Exosomal Secretion	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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