DDX11

Gene Name		DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Midbody Extracellular Vesicular Exosome
	Molecular Function	Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding ATP-dependent DNA Helicase Activity Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Sister Chromatid Cohesion Viral Process Endoplasmic Reticulum Unfolded Protein Response DNA Duplex Unwinding Cellular Protein Metabolic Process
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: KAT7 PFN2
Entrez ID		1663
HPRD ID		03095
Ensembl ID		ENSG00000013573
Uniprot IDs		Q2NKM7 Q96FC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Ruffle Assembly Histone H4-K12 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Ruffle Assembly Positive Regulation Of ATPase Activity Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synaptic Vesicle Transport Regulation Of ATPase Activity Positive Regulation Of Stress Fiber Assembly Histone H3 Acetylation Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Bundle Assembly Histone H4 Acetylation Regulation Of Stress Fiber Assembly Regulation Of Neurotransmitter Secretion Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation
Tagcloud ?		acidophilum chlr1 cpu cyclopurine deoxynucleosides ding distorting dnab fancj helicase helicases impeded ner pigmentosum recq recq1 sf1 sf2 sf4 taxpd thermoplasma translocating unwind unwinding uvrd wrn xeroderma xp xpd