TRIM31 and ZSCAN1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		TRIM31	ZSCAN1
Description		tripartite motif containing 31	zinc finger and SCAN domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Chromatin Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Ubiquitin-dependent Protein Catabolic Process Inflammatory Response Protein Ubiquitination Viral Release From Host Cell Negative Regulation Of Viral Transcription NLRP3 Inflammasome Complex Assembly Innate Immune Response Positive Regulation Of DNA-templated Transcription Host-mediated Suppression Of Symbiont Invasion Defense Response To Virus Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Antiviral Innate Immune Response Negative Regulation Of NLRP3 Inflammasome Complex Assembly	Regulation Of Transcription By RNA Polymerase II
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Beta-2 microglubulin plasma levels ( 23417110) Chronic obstructive pulmonary disease ( 33909500) Estimated glomerular filtration rate in diabetes ( 31451708) Haemorrhoidal disease ( 33888516) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Isovolumetric relaxation time ( 28394258) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252) Neuroticism ( 29255261) Prostate cancer ( 25217961) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 32771030) Takayasu arteritis ( 33308445) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes		26 interacting genes: CCT6A CFLAR EID3 IKBKG MAGEA1 MAGEA2B MAVS MKRN3 MNAT1 NSMCE4A RHBDF2 SYK TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2N UBE2W USP7 ZSCAN1	40 interacting genes: ANKRD55 APP ASH2L ATXN1 CDC5L CDK6 CNOT6L ERCC3 FXR2 GOPC GTF2E1 GTF2H1 HOPX INSM2 MED21 MED31 MED7 NFYC NPAS2 PLRG1 POLR2B POLR2D POLR2E PPARG PPL RFC1 SH2D2A SNW1 SSX3 SSX5 TAF7 TBX20 TIMELESS TRIM31 TTF2 ZKSCAN5 ZNF263 ZNF396 ZNF407 ZSCAN22
Entrez ID		11074	284312
HPRD ID		10281	15897
Ensembl ID		ENSG00000204616	ENSG00000152467
Uniprot IDs		Q2L6J1 Q9BZY9	Q8NBB4
PDB IDs		2YSJ 2YSL
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Polyubiquitination Post-translational Protein Modification Protein Ubiquitination Protein Modification Process TORC1 Signaling Protein Metabolic Process TOR Signaling Protein K11-linked Ubiquitination Protein K48-linked Ubiquitination Transferase Activity Negative Regulation Of TORC1 Signaling Protein K63-linked Ubiquitination Macromolecule Metabolic Process Negative Regulation Of TOR Signaling Ubiquitin Protein Ligase Binding Regulation Of TORC1 Signaling Ubiquitin Ligase Complex Regulation Of Metabolic Process Ubiquitin Protein Ligase Activity Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Modification-dependent Protein Catabolic Process DNA Damage Response Macromolecule Catabolic Process Regulation Of TOR Signaling ATP Binding Nucleotide Binding Innate Immune Response Regulation Of Nucleobase-containing Compound Metabolic Process Proteolysis Involved In Protein Catabolic Process Proteolysis Positive Regulation Of Autophagy Regulation Of Macromolecule Metabolic Process Regulation Of DNA-binding Transcription Factor Activity DNA Repair Cellular Response To Stress Defense Response To Symbiont Defense Response To Other Organism Response To Stress Nucleus Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization To Telomere	Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus DNA Binding Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process RNA Metabolic Process Positive Regulation Of Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process DNA-templated Transcription Nucleic Acid Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II, Core Complex Negative Regulation Of Transcription By RNA Polymerase II DNA Damage Response Negative Regulation Of RNA Metabolic Process Transcription Preinitiation Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Initiation By RNA Polymerase II Core Mediator Complex Regulation Of DNA-templated Transcription Initiation U2-type Catalytic Step 2 Spliceosome DNA-directed RNA Polymerase Activity Nucleoplasm Transcription Factor TFIID Complex Macromolecule Biosynthetic Process
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