TRIM31

Gene Name		tripartite motif containing 31
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Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Beta-2 microglubulin plasma levels ( 23417110)
Protein-protein Interactions		17 interactors: IKBKG MAGEA1 MAGEA2B MKRN3 MNAT1 TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2W USP7 ZSCAN1
Entrez ID		11074
HPRD ID		10281
Ensembl ID		ENSG00000204616
Uniprot IDs		Q2L6J1 Q9BZY9
PDB IDs		2YSJ 2YSL
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Cellular Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Protein K11-linked Ubiquitination Toll-like Receptor 4 Signaling Pathway Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Protein Modification Process Toll-like Receptor Signaling Pathway Cellular Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Macromolecule Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Innate Immune Response Response To Stress Protein Metabolic Process Cellular Metabolic Process Regulation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Innate Immune Response Immune Response-regulating Signaling Pathway Cellular Response To DNA Damage Stimulus Regulation Of Immune Response Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Protein Metabolic Process Positive Regulation Of Immune Response Cellular Response To Oxygen Levels
Tagcloud ?		advanced aims biological bronchial colony corresponding cyclin downregulation h1299 h157 hbe immumohistochemistry lines lung metastasis might nodal nsclc overexpression pattern plasmid regulator roles serve small suppressor tissues tnm transfection