GTF2A1L and ATF4

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		GTF2A1L	ATF4
Gene Name		general transcription factor IIA, 1-like	activating transcription factor 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Dendrite Membrane Nuclear Periphery Neuron Projection Lewy Body Core ATF1-ATF4 Transcription Factor Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein C-terminus Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cognition	Gluconeogenesis Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cellular Amino Acid Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Vascular Endothelial Growth Factor Production Endoplasmic Reticulum Unfolded Protein Response Circadian Regulation Of Gene Expression Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Response To Glucose Starvation Positive Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Neuron Apoptotic Process Cellular Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase I Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways			ATF4 activates genes PERK regulates gene expression ATF6-alpha activates chaperones ATF6-alpha activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 21151128)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		25 interactors: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3	65 interactors: APH1A APP ASB7 ATF2 ATF3 BATF BATF2 BATF3 BFSP2 BTRC CCDC106 CEBPA CEBPB CEBPE CEBPG CKAP4 CREB3 CREBZF DAPK3 DDIT3 DISC1 EGLN3 FOS FOSL1 GABBR2 GCC1 GOLGA1 GOLGA8EP GOLGA8F GPS2 GTF2A1L GTF2B GTF2F2 HAUS7 HK3 JUN JUNB KAT2B LDOC1 LMNB1 MAF MAFB MAP2K7 MDM2 MPZL2 NDC80 NEK6 NFE2 NFE2L1 NFE2L2 NFKBIA POLR2C PTCD3 REPS1 RPS6 SNAP29 SRA1 TBP TGM2 TREX2 TRIB3 TRIM24 TTR ZNF212 ZNF226
Entrez ID		11036	468
HPRD ID		05640	06817
Ensembl ID		ENSG00000242441	ENSG00000128272
Uniprot IDs		Q9UNN4	P18848 Q96AQ3
PDB IDs			1CI6
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Multicellular Organismal Development System Development Anatomical Structure Development Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Embryo Development Cell Differentiation Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Organ Development Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Organ Morphogenesis Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Generation Of Neurons Positive Regulation Of Cellular Metabolic Process Neurogenesis Cerebral Cortex Regionalization Positive Regulation Of Metabolic Process Neuron Differentiation Telencephalon Regionalization Pattern Specification Process Regulation Of Cell Differentiation Embryonic Organ Development Anterior/posterior Pattern Specification	Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To Stress Myeloid Cell Differentiation Leukocyte Differentiation Cellular Metabolic Process Response To Stress Apoptotic Process Cellular Response To Organic Substance Negative Regulation Of Biosynthetic Process Organ Development Myeloid Leukocyte Differentiation Defense Response Programmed Cell Death Immune System Process Response To Stimulus Cell Death Death Hemopoiesis Response To External Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			activates anticancer attenuated autophagy cebpb chip ddit4 depletion effectively elusive exo genomic greatly largely mitochondria mtorc1 nude pad pan perturbation potentials remain resolution responsive sesn2 triple unveiled xenograft yw3
Tagcloud (Difference) ?			activates anticancer attenuated autophagy cebpb chip ddit4 depletion effectively elusive exo genomic greatly largely mitochondria mtorc1 nude pad pan perturbation potentials remain resolution responsive sesn2 triple unveiled xenograft yw3
Tagcloud (Intersection) ?