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ATF4 and CEBPG
Number of citations of the paper that reports this interaction (PMID
1371974
)
10
Data Source:
BioGRID
(two hybrid, fluorescent resonance energy transfer)
HPRD
(in vitro)
ATF4
CEBPG
Gene Name
activating transcription factor 4
CCAAT/enhancer binding protein (C/EBP), gamma
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Microtubule Organizing Center
Dendrite Membrane
Nuclear Periphery
Neuron Projection
Lewy Body Core
ATF1-ATF4 Transcription Factor Complex
Nucleus
Nucleoplasm
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Transcription Factor Binding Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Protein C-terminus Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Double-stranded DNA Binding
Protein Binding
Transcription Factor Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Biological Process
Gluconeogenesis
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Cellular Amino Acid Metabolic Process
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Gamma-aminobutyric Acid Signaling Pathway
Positive Regulation Vascular Endothelial Growth Factor Production
Endoplasmic Reticulum Unfolded Protein Response
Circadian Regulation Of Gene Expression
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Cellular Response To Glucose Starvation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Potassium Ion Transport
Positive Regulation Of Neuron Apoptotic Process
Cellular Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase I Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Oxidative Stress-induced Neuron Death
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Liver Development
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Immune Response
MRNA Metabolic Process
B Cell Differentiation
Natural Killer Cell Mediated Cytotoxicity
Enucleate Erythrocyte Differentiation
Positive Regulation Of DNA Binding
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Interferon-gamma Biosynthetic Process
Positive Regulation Of DNA Repair
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
ATF4 activates genes
PERK regulates gene expression
ATF6-alpha activates chaperones
ATF6-alpha activates chaperone genes
Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
65 interactors:
APH1A
APP
ASB7
ATF2
ATF3
BATF
BATF2
BATF3
BFSP2
BTRC
CCDC106
CEBPA
CEBPB
CEBPE
CEBPG
CKAP4
CREB3
CREBZF
DAPK3
DDIT3
DISC1
EGLN3
FOS
FOSL1
GABBR2
GCC1
GOLGA1
GOLGA8EP
GOLGA8F
GPS2
GTF2A1L
GTF2B
GTF2F2
HAUS7
HK3
JUN
JUNB
KAT2B
LDOC1
LMNB1
MAF
MAFB
MAP2K7
MDM2
MPZL2
NDC80
NEK6
NFE2
NFE2L1
NFE2L2
NFKBIA
POLR2C
PTCD3
REPS1
RPS6
SNAP29
SRA1
TBP
TGM2
TREX2
TRIB3
TRIM24
TTR
ZNF212
ZNF226
22 interactors:
ATF2
ATF3
ATF4
ATF5
BATF
BATF2
BATF3
CEBPA
CEBPB
CEBPD
CEBPE
CREB3
CREB3L3
DBP
DDIT3
FOS
FOSL1
GTF2F2
JUN
MLLT6
PLAU
POLR2M
Entrez ID
468
1054
HPRD ID
06817
00738
Ensembl ID
ENSG00000128272
ENSG00000153879
Uniprot IDs
P18848
Q96AQ3
P53567
PDB IDs
1CI6
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Gene Expression
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Response To Stress
Myeloid Cell Differentiation
Leukocyte Differentiation
Cellular Metabolic Process
Response To Stress
Apoptotic Process
Cellular Response To Organic Substance
Negative Regulation Of Biosynthetic Process
Organ Development
Myeloid Leukocyte Differentiation
Defense Response
Programmed Cell Death
Immune System Process
Response To Stimulus
Cell Death
Death
Hemopoiesis
Response To External Stimulus
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Metabolic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Cellular Metabolic Process
Response To External Stimulus
Myeloid Leukocyte Differentiation
Response To Biotic Stimulus
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Response To Stress
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Topologically Incorrect Protein
Myeloid Cell Differentiation
Response To Unfolded Protein
Response To Other Organism
Organ Development
Cellular Response To Stress
Leukocyte Differentiation
Defense Response
Myeloid Dendritic Cell Differentiation
System Development
Myeloid Dendritic Cell Activation
Cellular Response To Organic Substance
Response To Extracellular Stimulus
Cellular Metabolic Process
Tagcloud
?
activates
anticancer
attenuated
autophagy
cebpb
chip
ddit4
depletion
effectively
elusive
exo
genomic
greatly
largely
mitochondria
mtorc1
nude
pad
pan
perturbation
potentials
remain
resolution
responsive
sesn2
triple
unveiled
xenograft
yw3
Tagcloud (Difference)
?
activates
anticancer
attenuated
autophagy
cebpb
chip
ddit4
depletion
effectively
elusive
exo
genomic
greatly
largely
mitochondria
mtorc1
nude
pad
pan
perturbation
potentials
remain
resolution
responsive
sesn2
triple
unveiled
xenograft
yw3
Tagcloud (Intersection)
?