GTF2A1L and SIX6

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		GTF2A1L	SIX6
Gene Name		general transcription factor IIA, 1-like	SIX homeobox 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Nucleus
	Molecular Function	DNA Binding Transcription Coactivator Activity	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cognition	Visual Perception Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 21151128)	Glaucoma (primary open-angle) ( 22419738 22570617) Height ( 20881960) Refractive error ( 23396134)
Protein-Protein Interactions		25 interactors: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3	3 interactors: AES GTF2A1L TLE1
Entrez ID		11036	4990
HPRD ID		05640	07557
Ensembl ID		ENSG00000242441
Uniprot IDs		Q9UNN4	O95475 Q6P051
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Multicellular Organismal Development System Development Anatomical Structure Development Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Embryo Development Cell Differentiation Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Organ Development Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Organ Morphogenesis Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Generation Of Neurons Positive Regulation Of Cellular Metabolic Process Neurogenesis Cerebral Cortex Regionalization Positive Regulation Of Metabolic Process Neuron Differentiation Telencephalon Regionalization Pattern Specification Process Regulation Of Cell Differentiation Embryonic Organ Development Anterior/posterior Pattern Specification	Regulation Of Anoikis Negative Regulation Of Wnt Signaling Pathway Wnt Signaling Pathway Positive Regulation Of Anoikis Regulation Of Wnt Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Anoikis RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Response To Cytokine Stimulus Organ Morphogenesis Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Binding Negative Regulation Of Signaling Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-1 Regulation Of Apoptotic Process Regulation Of Cell Death Negative Regulation Of Binding Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Response To Extracellular Stimulus DNA-templated Transcription, Initiation Regulation Of Canonical Wnt Signaling Pathway
Tagcloud ?			as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Difference) ?			as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Intersection) ?