GTF2A1L and HOXA5

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		GTF2A1L	HOXA5
Gene Name		general transcription factor IIA, 1-like	homeobox A5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Nucleus
	Molecular Function	DNA Binding Transcription Coactivator Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cognition	Respiratory System Process Transcription, DNA-templated Anterior/posterior Pattern Specification Positive Regulation Of Receptor Biosynthetic Process Cell Migration Negative Regulation Of Angiogenesis Thyroid Gland Development Regulation Of Mammary Gland Epithelial Cell Proliferation Multicellular Organism Growth Positive Regulation Of Apoptotic Process Positive Regulation Of Myeloid Cell Differentiation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lung Alveolus Development Embryonic Skeletal System Morphogenesis Bronchiole Development Epithelial Tube Branching Involved In Lung Morphogenesis Lung Goblet Cell Differentiation Lung-associated Mesenchyme Development Trachea Cartilage Morphogenesis Intestinal Epithelial Cell Maturation Mesenchymal-epithelial Cell Signaling Mammary Gland Epithelial Cell Differentiation Mammary Gland Alveolus Development Cell-cell Signaling Involved In Mammary Gland Development
Pathways
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 21151128)
Protein-Protein Interactions		25 interactors: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3	11 interactors: CDX4 DDIT3 FOXA2 FOXO1 GTF2A1L MEIS1 PBX1 PRMT6 SMAD1 TWIST1 ZNF408
Entrez ID		11036	3202
HPRD ID		05640	00840
Ensembl ID		ENSG00000242441	ENSG00000106004
Uniprot IDs		Q9UNN4	P20719
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Multicellular Organismal Development System Development Anatomical Structure Development Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Embryo Development Cell Differentiation Positive Regulation Of Gene Expression Anatomical Structure Morphogenesis Organ Development Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Organ Morphogenesis Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Generation Of Neurons Positive Regulation Of Cellular Metabolic Process Neurogenesis Cerebral Cortex Regionalization Positive Regulation Of Metabolic Process Neuron Differentiation Telencephalon Regionalization Pattern Specification Process Regulation Of Cell Differentiation Embryonic Organ Development Anterior/posterior Pattern Specification	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Negative Regulation Of Gene Expression Cardiovascular System Development Pattern Specification Process Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Cell Development Blood Vessel Development Vasculature Development Regulation Of Neuron Differentiation Negative Regulation Of Neuron Differentiation Regulation Of Ossification Skeletal System Development System Development Embryo Development Cellular Metabolic Process
Tagcloud ?			aberrant abilities abstract arrests committed depending drives erythrocyte erythroid erythropoiesis expanding g0 hsc hscs inappropriate lineage modifies mpps multipotency multipotent pool predominance preferentially progenitor progenitors renewal seq shrinks sustain
Tagcloud (Difference) ?			aberrant abilities abstract arrests committed depending drives erythrocyte erythroid erythropoiesis expanding g0 hsc hscs inappropriate lineage modifies mpps multipotency multipotent pool predominance preferentially progenitor progenitors renewal seq shrinks sustain
Tagcloud (Intersection) ?