EMSY and CLVS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMSY	CLVS2
Description		EMSY transcriptional repressor, BRCA2 interacting	clavesin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response	Lysosome Organization
Pathways			Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Allergic rhinitis ( 31361310) Asthma ( 29273806 31361310 31959851 34103634) Asthma (adult onset) ( 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Eczema ( 31361310) Eosinophil count ( 29403010) Eosinophilic esophagitis ( 34506852) Type 1 diabetes ( 34012112)	Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		14 interacting genes: AIDA AKT1 BRCA2 CBX1 CLVS2 DDIT3 DISC1 GET3 H3-4 LIX1 PSMA1 ZMYND11 ZNF131 ZNF646	16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2
Entrez ID		56946	134829
HPRD ID		10544	16666
Ensembl ID		ENSG00000158636	ENSG00000146352
Uniprot IDs		Q7Z589	Q5SYC1
PDB IDs		1UTU 1UZ3 2FMM
Enriched GO Terms of Interacting Partners?		PERK-mediated Unfolded Protein Response	Catalytic Activity Transition Metal Ion Binding Glutathione Transferase Activity Identical Protein Binding Cytosol Maleylacetoacetate Isomerase Activity Ethanolamine-phosphate Cytidylyltransferase Activity FMN Adenylyltransferase Activity FAD Biosynthetic Process FAD Diphosphatase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?