SUB1 and POU2AF1

Number of citations of the paper that reports this interaction (PubMedID 9632764)
60

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		SUB1	POU2AF1
Description		SUB1 regulator of transcription	POU class 2 homeobox associating factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Extracellular Exosome	Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding POU Domain Binding
	Biological Process	RNA Polymerase II Promoter Clearance Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) PR interval ( 32439900)	Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)
Interacting Genes		24 interacting genes: ADAP1 APP CBX5 CEBPA CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 OTUD5 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST RNF10 SDCBP SP1 TAF1 TBP TP53	54 interacting genes: CCDC120 CIMIP2B DGCR6L FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581
Entrez ID		10923	5450
HPRD ID		02737	03126
Ensembl ID		ENSG00000113387	ENSG00000110777
Uniprot IDs		P53999 Q6IBA2	Q16633
PDB IDs		1PCF 2C62 2PHE 4USG 6YCS 7E4W	1CQT
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Binding Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Repressor Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process STAT Family Protein Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Nucleic Acid Metabolic Process Chromatin Organization Rhythmic Process Euchromatin MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Xenobiotic Stimulus RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of DNA-templated Transcription Initiation Cellular Response To Radiation DNA-binding Transcription Factor Binding	DNA-binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Pattern Specification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regionalization Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Serotonin Transport Positive Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Pyrimidine Nucleoside Transmembrane Transporter Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Intermediate Filament Anterior/posterior Pattern Specification Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Putrescine Transmembrane Transporter Activity Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Nephron Tubule Development Embryonic Morphogenesis Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Renal Tubule Development Kidney Epithelium Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Embryonic Hindlimb Morphogenesis Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport
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