POU2AF1 and NAB1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		POU2AF1	NAB1
Description		POU class 2 homeobox associating factor 1	NGFI-A binding protein 1
Image
GO Annotations	Cellular Component	Nucleus RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding POU Domain Binding	Transcription Coregulator Activity
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Endochondral Ossification Regulation Of DNA-templated Transcription Schwann Cell Differentiation Myelination Regulation Of Epidermis Development Negative Regulation Of DNA-templated Transcription
Pathways			NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Autoimmune traits (pleiotropy) ( 30572963) Bone mineral density (Ward's triangle area) ( 27397699) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Multiple sclerosis ( 31604244) Polymyositis ( 26362759) Primary biliary cholangitis ( 26394269) Pulse pressure ( 27841878) Rheumatoid arthritis ( 30572963) Systemic lupus erythematosus ( 33536424) Systemic sclerosis ( 31672989) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		54 interacting genes: CCDC120 CIMIP2B DGCR6L FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	2 interacting genes: EGR1 POU2AF1
Entrez ID		5450	4664
HPRD ID		03126	02881
Ensembl ID		ENSG00000110777	ENSG00000138386
Uniprot IDs		Q16633	A8K8T1 B4DKG1 B8ZZS2 Q13506
PDB IDs		1CQT	2YUF
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Pattern Specification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regionalization Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Serotonin Transport Positive Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Pyrimidine Nucleoside Transmembrane Transporter Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Intermediate Filament Anterior/posterior Pattern Specification Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Putrescine Transmembrane Transporter Activity Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Nephron Tubule Development Embryonic Morphogenesis Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Renal Tubule Development Kidney Epithelium Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Embryonic Hindlimb Morphogenesis Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport	Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Cellular Response To Mycophenolic Acid Glomerular Mesangial Cell Proliferation Cellular Response To Interleukin-8 Lymphocyte Differentiation Circadian Temperature Homeostasis Cellular Response To Heparin Regulation Of Progesterone Biosynthetic Process Mononuclear Cell Differentiation Hemi-methylated DNA-binding Leukocyte Differentiation POU Domain Binding Response To Heparin Double-stranded Methylated DNA Binding Lymphocyte Activation Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Cytokine Production Positive Regulation Of Cell Proliferation Involved In Kidney Development Leukocyte Activation Positive Regulation Of Hormone Biosynthetic Process Germinal Center B Cell Differentiation Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Estrous Cycle Locomotor Rhythm Cell Activation Positive Regulation Of Gene Expression Via Chromosomal CpG Island Demethylation Ovulation Cycle Regulation Of Cytokine Production Circadian Behavior Regulation Of Ketone Biosynthetic Process Regulation Of Hormone Biosynthetic Process Regulation Of Protein Sumoylation Rhythmic Behavior Histone Acetyltransferase Binding Interleukin-1-mediated Signaling Pathway Cellular Response To Gamma Radiation Mature B Cell Differentiation Involved In Immune Response Mature B Cell Differentiation Regulation Of Hormone Metabolic Process Temperature Homeostasis Positive Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Response To Gamma Radiation Positive Regulation Of MiRNA Transcription Skeletal Muscle Cell Differentiation Positive Regulation Of Interleukin-1 Beta Production Response To Ischemia
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?