SUB1 and CSTF2

Number of citations of the paper that reports this interaction (PMID 11389848)
48

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SUB1	CSTF2
Gene Name		SUB1 homolog (S. cerevisiae)	cleavage stimulation factor, 3 pre-RNA, subunit 2, 64kDa
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Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nucleolus Extracellular Vesicular Exosome	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Cleavage Body
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding Transcription Coactivator Activity Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter SMAD Protein Signal Transduction	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ADAP1 APP CBX5 CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST SP1 TAF1 TBP	23 interactors: APP BAG6 C14orf1 CHD3 CSTF3 DDX1 ECH1 EEF1G FEZ1 HGS IKBKAP IMMT KAT5 KIAA1377 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341
Entrez ID		10923	1478
HPRD ID		02737	02652
Ensembl ID		ENSG00000113387	ENSG00000101811
Uniprot IDs		P53999 Q6IBA2	E7EWR4 P33240
PDB IDs		1PCF 2C62 2PHE	1P1T 2J8P
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Viral Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of Viral Process Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Interaction With Symbiont Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Response To Stress MRNA Processing Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Regulation Of Cellular Process MRNA Metabolic Process Nucleotide-excision Repair	MRNA Polyadenylation Gene Expression RNA Polyadenylation RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Processing MRNA 3'-end Processing Regulation Of Protein Metabolic Process MRNA Metabolic Process RNA 3'-end Processing Regulation Of Gene Expression Regulation Of Metabolic Process RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transcription Elongation From RNA Polymerase II Promoter Transcription, RNA-templated Synaptic Growth At Neuromuscular Junction Nitrogen Compound Metabolic Process Regulation Of Dendrite Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway DNA Duplex Unwinding DNA Geometric Change Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process RNA Splicing Regulation Of Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition
Tagcloud ?		biosynthetic choline coactivators demethylation dot1 ecm5 gcn5 gis1 icre ino2 ino4 inositol jhd1 jhd2 lys36 med15 med18 med19 med2 med3 mediator methyltransferase modify phospholipid recruit rph1 set1 set2 snf1
Tagcloud (Difference) ?		biosynthetic choline coactivators demethylation dot1 ecm5 gcn5 gis1 icre ino2 ino4 inositol jhd1 jhd2 lys36 med15 med18 med19 med2 med3 mediator methyltransferase modify phospholipid recruit rph1 set1 set2 snf1
Tagcloud (Intersection) ?