POU2AF1 and RAMAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POU2AF1	RAMAC
Description		POU class 2 homeobox associating factor 1	RNA guanine-7 methyltransferase activating subunit
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GO Annotations	Cellular Component	Nucleus RNA Polymerase II Transcription Regulator Complex	Nucleus MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding POU Domain Binding	RNA Binding Protein Binding Enzyme Activator Activity Molecular Function Activator Activity
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	7-methylguanosine MRNA Capping MRNA Processing RNA 5'-cap (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)
Interacting Genes		54 interacting genes: CCDC120 CIMIP2B DGCR6L FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 UBC USP54 VPS37C WWOX
Entrez ID		5450	83640
HPRD ID		03126	12845
Ensembl ID		ENSG00000110777	ENSG00000169612
Uniprot IDs		Q16633	Q9BTL3
PDB IDs		1CQT	5E8J
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Pattern Specification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regionalization Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Serotonin Transport Positive Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Pyrimidine Nucleoside Transmembrane Transporter Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Intermediate Filament Anterior/posterior Pattern Specification Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Putrescine Transmembrane Transporter Activity Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Nephron Tubule Development Embryonic Morphogenesis Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Renal Tubule Development Kidney Epithelium Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Embryonic Hindlimb Morphogenesis Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport	Identical Protein Binding Protein Binding Spliceosomal Complex Structural Constituent Of Skin Epidermis RNA Splicing Intermediate Filament Regulation Of RNA Splicing Nucleic Acid Binding Keratin Filament Transcription Coactivator Activity MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome CD4 Receptor Binding RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of MRNA Processing Ribonucleoprotein Complex RNA Binding Positive Regulation Of Apoptotic Signaling Pathway
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