LBX1 and RBL2

Number of citations of the paper that reports this interaction (PMID 16600870)
9

Data Source:
BioGRID (two hybrid)

		LBX1	RBL2
Gene Name		ladybird homeobox 1	retinoblastoma-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	DNA Binding Protein Binding
	Biological Process	Heart Looping Transcription, DNA-templated Muscle Organ Development Negative Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Spinal Cord Motor Neuron Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spinal Cord Association Neuron Specification Negative Regulation Of Neuron Differentiation Neuron Fate Determination	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle
Pathways			Cyclin D associated events in G1 G1 Phase G0 and Early G1 Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Scoliosis ( 22019779)
Protein-Protein Interactions		1 interactors: RBL2	42 interactors: BRCA1 BRF1 BRF2 CCNA1 CCNA2 CCND1 CCND3 CCNE1 CDK2 CDK4 CDK6 CREG1 DCTN1 DGKZ E2F4 E2F5 EZH2 GRAMD4 HBP1 HDAC1 ID2 LBX1 LDHC MCM7 MNDA PCBD1 PHB PPP2CA RAF1 RBBP8 RBBP9 RINT1 SKP2 SMARCA4 SNW1 SUV39H1 SUV420H2 TAF1 TOP1 UBTF USP4 XBP1
Entrez ID		10660	5934
HPRD ID		09178	01576
Ensembl ID			ENSG00000103479
Uniprot IDs		P52954	Q08999 Q8NE70
PDB IDs
Enriched GO Terms of Interacting Partners?			Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cell Cycle Process Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cell Division Regulation Of Cell Proliferation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle RNA Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Chromatin Organization Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Process DNA-templated Transcription, Initiation Cellular Metabolic Process Organelle Organization Regulation Of Cellular Protein Metabolic Process Chromosome Organization Cellular Response To Stress Regulation Of Protein Kinase Activity
Tagcloud ?		10q24 22x10 94x10 ais ancestral asian boundaries cohorts collaborative consortium crest deformity encompassing ethnicities firmly genders gwas homeobox icsg ladybird omim orthologous refined replicated rotational rs11190870 scoliosis specification tubes	arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn
Tagcloud (Difference) ?		10q24 22x10 94x10 ais ancestral asian boundaries cohorts collaborative consortium crest deformity encompassing ethnicities firmly genders gwas homeobox icsg ladybird omim orthologous refined replicated rotational rs11190870 scoliosis specification tubes	arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn
Tagcloud (Intersection) ?