SOX10 and HOXA3

Number of citations of the paper that reports this interaction (PMID 16582099)
41

Data Source:
HPRD (two hybrid)

		SOX10	HOXA3
Gene Name		SRY (sex determining region Y)-box 10	homeobox A3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extrinsic Component Of Mitochondrial Outer Membrane	Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	In Utero Embryonic Development Neural Crest Cell Migration Positive Regulation Of Neuroblast Proliferation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Peripheral Nervous System Development Anatomical Structure Morphogenesis Positive Regulation Of Gliogenesis Melanocyte Differentiation Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Maturation Enteric Nervous System Development Digestive Tract Morphogenesis Developmental Growth Oligodendrocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway	Angiogenesis Blood Vessel Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Specification Of Organ Position Glossopharyngeal Nerve Morphogenesis Thyroid Gland Development Thymus Development Organ Formation Embryonic Skeletal System Morphogenesis Cartilage Development Parathyroid Gland Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ALX4 CDK6 CEBPA DLX5 EGR2 EXOC5 HHEX HIVEP1 HOXA3 HOXC4 JUN MEOX1 NMI OLIG2 PAX3 PAX6 POU3F2 POU3F3 POU5F1 PRRX1 PRRX2 SP1 SUMO1 SUMO2 SUMO3 TCF12 UBE2I UTF1	9 interactors: ALX4 ARPC3 POT1 PWP1 SEC23B SOX10 TERF1 TINF2 ZDHHC17
Entrez ID		6663	3200
HPRD ID		03752	00842
Ensembl ID		ENSG00000100146	ENSG00000105997
Uniprot IDs		B4DV62 P56693	A4D182 B3KPN8 O43365
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Tissue Development Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process System Development Macromolecule Biosynthetic Process Protein Sumoylation Embryonic Morphogenesis Anatomical Structure Development Embryonic Organ Development Embryo Development Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Cellular Nitrogen Compound Metabolic Process Pattern Specification Process Embryonic Organ Morphogenesis Organ Morphogenesis Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Cell Proliferation Gland Development	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of DNA Replication Regulation Of Telomerase Activity RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Protein Polymerization Negative Regulation Of Biosynthetic Process Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Formation Via Telomerase Digestive Tract Development Positive Regulation Of DNA Metabolic Process Digestive System Development Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Positive Regulation Of Protein Complex Assembly Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cytoskeleton Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication
Tagcloud ?		abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected	a11 a13 a7 a9 bases ccctc cluster colinearity controller ctcf facilitates h3k27me3 hoxa9 locus looping loops organized polycomb positional prc2 repressive sequentially silencing silent stabilization trimethylated vertebrate
Tagcloud (Difference) ?		abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected	a11 a13 a7 a9 bases ccctc cluster colinearity controller ctcf facilitates h3k27me3 hoxa9 locus looping loops organized polycomb positional prc2 repressive sequentially silencing silent stabilization trimethylated vertebrate
Tagcloud (Intersection) ?