MKRN2 and C1orf109

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MKRN2	C1orf109
Gene Name		makorin ring finger protein 2	chromosome 1 open reading frame 109
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	Biological_process Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: C1orf109 GNB2L1 NDN RBCK1 UBE2D1 UBE2D4 UBE2K	44 interactors: AES C1orf94 CCDC36 CEP55 CINP CRX CSNK2A1 GOLGA2 IKZF1 IKZF3 KATNAL1 KIFC3 KRT13 KRT19 KRT31 KRT40 LDOC1 LZTS2 MEOX2 MKRN2 MTUS2 NECAB2 PDE4DIP PHC2 PLK4 PPP1R12C REL RINT1 RNF41 SDCBP SPAG5 SPERT STX11 TADA2A TCF12 TCF4 TFIP11 TRAF1 TRIM42 TRIM54 USHBP1 VPS52 ZBED1 ZNF398
Entrez ID		23609	54955
HPRD ID		09761	07918
Ensembl ID		ENSG00000075975	ENSG00000116922
Uniprot IDs		B4DPR4 Q9H000	B4DRQ5 Q9NX04
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Protein Linear Polyubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Apoptotic Signaling Pathway Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Cell Division Protein K6-linked Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Negative Regulation Of Transferase Activity Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Mitochondrial Depolarization Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Phagocytosis Protein Metabolic Process Negative Regulation Of Necroptotic Process Respiratory System Process Negative Regulation Of Necrotic Cell Death Cellular Protein Modification Process Regulation Of Necroptotic Process Negative Regulation Of Protein Tyrosine Kinase Activity Proteolysis Regulation Of Mitochondrial Depolarization Positive Regulation Of Protein Oligomerization Immune Response-regulating Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus Protein K11-linked Ubiquitination	Cell Cycle Mitotic Cell Cycle Microtubule Severing Developmental Process Transcription, DNA-templated RNA Biosynthetic Process Mitotic Cell Cycle Process Multicellular Organismal Development Anatomical Structure Development Cell Cycle Process Positive Regulation Of Organelle Assembly Wnt Signaling Pathway Organ Development Microtubule-based Process Regulation Of Wnt Signaling Pathway Cytoskeleton Organization Organelle Organization Regulation Of Microtubule Cytoskeleton Organization System Development Cell Differentiation Involved In Embryonic Placenta Development RNA Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Transcription From RNA Polymerase II Promoter Regulation Of Lymphocyte Differentiation Regulation Of Transcription, DNA-templated Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of Organelle Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of Microtubule-based Process Regulation Of RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Tissue Development Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Division Negative Regulation Of Protein Binding Catenin Import Into Nucleus Positive Regulation Of Centriole Replication Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization
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