SYT11

Gene Name		synaptotagmin XI
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane
	Molecular Function	Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Transport Negative Regulation Of Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 21292315)
Protein-protein Interactions		4 interactors: APPBP2 PARK2 SGTA SYNCRIP
Entrez ID		23208
HPRD ID		12289
Ensembl ID		ENSG00000132718
Uniprot IDs		Q9BT88
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Protein Linear Polyubiquitination Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion CRD-mediated MRNA Stabilization Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Aggresome Assembly Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Zinc Ion Homeostasis Negative Regulation Of Release Of Cytochrome C From Mitochondria Response To Manganese Ion Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Viral Process Cellular Response To Ammonium Ion Regulation Of Dopamine Secretion Cellular Response To Toxic Substance Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoamine Transport Mitochondrial Fission MRNA Stabilization Cellular Response To Catecholamine Stimulus Negative Regulation Of Oxidative Stress-induced Cell Death Startle Response Mitochondrion Degradation Dopamine Metabolic Process Positive Regulation Of Cytokine-mediated Signaling Pathway
Tagcloud ?		ago2 assigned c2 c2a c2b calcium constituting fmrp golgi insensitive interacted isoforms link micrornas partners q repeats risc silencing snare snd snd1 synaptotagmin synaptotagmins tandem traffic transmembrane vesicles vti1a