SEC23B and TMED2

Number of citations of the paper that reports this interaction (PMID 9472029)
82

Data Source:
BioGRID (unspecified method)

		SEC23B	TMED2
Gene Name		Sec23 homolog B (S. cerevisiae)	transmembrane emp24 domain trafficking protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endomembrane System Membrane COPII Vesicle Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Zinc Ion Binding	Protein Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport	Maternal Placenta Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Negative Regulation Of GTPase Activity Cargo Loading Into Vesicle COPI Coating Of Golgi Vesicle COPII Vesicle Coating Embryonic Morphogenesis Protein Targeting To Plasma Membrane
Pathways			Pre-NOTCH Processing in Golgi Signaling by NOTCH Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CPSF7 DTX2 FATE1 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 SEC24C SEC24D SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1	9 interactors: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10
Entrez ID		10483	10959
HPRD ID		11543	17984
Ensembl ID		ENSG00000101310	ENSG00000086598
Uniprot IDs		B4DJW8 Q15437	Q15363 Q6FHT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting COPII Vesicle Coating COPII-coated Vesicle Budding Membrane Budding COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization ER To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Post-translational Protein Modification Cargo Loading Into Vesicle Golgi Organization Protein N-linked Glycosylation Via Asparagine Protein Glycosylation Macromolecule Glycosylation Protein N-linked Glycosylation Glycosylation Positive Regulation Of Viral Genome Replication Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Complex Assembly Organelle Organization Negative Regulation Of Viral Genome Replication Carbohydrate Metabolic Process Nuclear Speck Organization Biphenyl Catabolic Process Bilirubin Conjugation Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Transport Cellular Component Assembly Protein Localization Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Establishment Of Localization In Cell Cellular Protein Localization RNA Splicing	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Protein Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Intracellular Transport Membrane Organization Intracellular Protein Transport Organelle Localization Establishment Of Localization In Cell Cellular Protein Localization Cellular Localization Vesicle-mediated Transport Organelle Organization Golgi Organization Transport Endomembrane System Organization ER To Golgi Vesicle-mediated Transport Secretion Activation Of Ral GTPase Activity Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Positive Regulation Of Glucose Import In Response To Insulin Stimulus Mitotic Cell Cycle Positive Regulation Of Ral GTPase Activity Regulation Of Ral Protein Signal Transduction Pancreatic Juice Secretion Cargo Loading Into Vesicle Negative Regulation Of Dendrite Morphogenesis Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Vesicle Fusion Positive Regulation Of Glycogen Biosynthetic Process Peripheral Nervous System Myelin Maintenance Negative Regulation Of Dendrite Development Long Term Synaptic Depression Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Cellular Copper Ion Homeostasis COPII Vesicle Coating
Tagcloud ?		aflatoxin biogenesis btf3 calreticulin compartments confer dissected dynactin eef immunoblot nodules nucleolin nucleophosmin oncomine p450 participates peptidase pgrmc1 pur ribosome rough sec13 subcellular ter traffic transitional tripeptidyl unexpectedly usp10	androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular
Tagcloud (Difference) ?		aflatoxin biogenesis btf3 calreticulin compartments confer dissected dynactin eef immunoblot nodules nucleolin nucleophosmin oncomine p450 participates peptidase pgrmc1 pur ribosome rough sec13 subcellular ter traffic transitional tripeptidyl unexpectedly usp10	androgens benzoate biphasic chosen clarified constantly converted defeminization defeminized dimorphism eb encording estradiol hcrt hypothalamus klc1 masculinization masculinized nedd4 neuroprotection orexin peaked perinatal prostaglandin ptgds rodents semiquantitative seventy testicular
Tagcloud (Intersection) ?