SEC23B and PRRC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SEC23B	PRRC1
Description		SEC23 homolog B, COPII component	proline rich coiled-coil 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Cytoplasm Golgi Apparatus
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport COPII-coated Vesicle Cargo Loading COPII-coated Vesicle Budding	Epithelial Structure Maintenance
Pathways
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS		Refractive error ( 32231278)	Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 RIN1 SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UBA52 UBC UGT1A1	5 interacting genes: APP OGT PIN1 SEC23B TSG101
Entrez ID		10483	133619
HPRD ID		11543	14052
Ensembl ID		ENSG00000101310	ENSG00000164244
Uniprot IDs		A0A2R8YFH5 Q15437	Q96M27
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Vesicle Cargo Loading Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Vesicle Transport COPII-coated ER To Golgi Transport Vesicle ER To Golgi Transport Vesicle Membrane Protein Modification Process Transport Vesicle Vesicle Coating Protein Ubiquitination Golgi Organization Maintenance Of Protein Localization In Organelle Cis-Golgi Network Endoplasmic Reticulum Protein Modification By Small Protein Conjugation Maintenance Of Protein Location In Cell Maintenance Of Protein Location Intracellular Protein Transport Maintenance Of Location In Cell COPI-coated Vesicle Post-translational Protein Modification Protein Tag Activity Maintenance Of Location COPII Vesicle Coat COPI-coated Vesicle Membrane Vesicle-mediated Transport Zymogen Granule Membrane Trans-Golgi Network Transport Vesicle COPII-coated Vesicle Cargo Loading Golgi Membrane In Utero Embryonic Development Chordate Embryonic Development COPII Vesicle Coating Golgi Apparatus Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Viral Protein Processing Endoplasmic Reticulum Exit Site Positive Regulation Of Viral Genome Replication Protein Transport Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Metabolic Process	Regulation Of Phosphorus Metabolic Process Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Protein-containing Complex Organization Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Protein Catabolic Process Regulation Of Protein Localization Negative Regulation Of Cell Communication Cis-trans Isomerase Activity Protein Localization To Vacuole Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Lipoprotein Particle Regulation Of Protein Localization To Nucleus Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Modification Process Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Negative Regulation Of Protein Catabolic Process Macroautophagy Positive Regulation Of Ubiquitin-dependent Endocytosis Positive Regulation Of Viral Budding Via Host ESCRT Complex Protein O-acetylglucosaminyltransferase Activity Regulation Of Synapse Assembly Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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