PRMT5 and RBM23

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		PRMT5	RBM23
Gene Name		protein arginine methyltransferase 5	RNA binding motif protein 23
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Methylosome	Nucleus Membrane
	Molecular Function	Core Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Ribonucleoprotein Complex Binding	Nucleotide Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spliceosomal SnRNP Assembly Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Mitotic Nuclear Division Cell Proliferation Gene Expression Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Circadian Regulation Of Gene Expression NcRNA Metabolic Process Peptidyl-arginine N-methylation Endothelial Cell Activation Histone H4-R3 Methylation	MRNA Processing
Pathways		Chromatin modifying enzymes snRNP Assembly Chromatin organization Metabolism of non-coding RNA RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		67 interactors: ARGLU1 CALU CAPN1 CCAR2 CDYL2 CLK1 CLK3 CLNS1A COPRS CTDP1 DIO3 DNMT3A EZH2 FAM76B GRHL3 GTPBP2 H3F3C HIST1H3A HIST1H4A HIST2H2AC HOXC4 ING5 JAK1 JAK2 JAK3 LDHAL6B LENG8 LUC7L MAGEB2 MBP MCRS1 MEF2D MYOD1 MYOG NELFCD NUDCD2 OLA1 PHYHIP PRPF38A RBM23 RSRP1 SF3A3 SIN3A SLU7 SMARCA2 SMARCB1 SMARCC1 SMARCE1 SNRNP70 SNRPB SNRPD1 SNRPD3 SPAG8 SSTR1 SUPT5H TRIB3 TYK2 WDR5 WDR77 YWHAG YWHAQ YWHAZ ZDHHC17 ZNF2 ZNF224 ZNF436 ZUFSP	24 interactors: BHLHE40 CDK6 CHERP ESR1 FAM9B GTF3C1 KIAA1377 MAGEA11 MAGED1 MED31 PGR POLA2 PRMT5 PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 SRPK2 TRIM27 TUBA4A
Entrez ID		10419	55147
HPRD ID		04955	15227
Ensembl ID		ENSG00000100462	ENSG00000100461
Uniprot IDs		O14744	G3XAP0 Q86U06
PDB IDs		4GQB	2CQ4 2DNZ
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Chromatin Modification Regulation Of RNA Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated MRNA Metabolic Process RNA Splicing RNA Biosynthetic Process RNA Processing Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Transcription, DNA-templated MRNA Splicing, Via Spliceosome Regulation Of Nucleic Acid-templated Transcription RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Positive Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Histone Modification Positive Regulation Of Macromolecule Biosynthetic Process Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Ribonucleoprotein Complex Biogenesis Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-tyrosine Autophosphorylation Peptidyl-amino Acid Modification Positive Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Chromatin Remodeling Regulation Of Metabolic Process Positive Regulation Of Viral Transcription Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Nucleosome Disassembly Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process	RNA Splicing RNA Processing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Metabolic Process Gene Expression Regulation Of MRNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of Cell Proliferation Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression Circadian Rhythm Mammary Gland Branching Involved In Pregnancy Regulation Of RNA Metabolic Process Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Viral Process Circadian Regulation Of Gene Expression Regulation Of Metabolic Process Mitotic Cell Cycle Phase Transition Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Phase Transition Regulation Of Fibroblast Proliferation Regulation Of Circadian Rhythm Cellular Macromolecule Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Macromolecule Biosynthetic Process Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Viral Genome Replication Entrainment Of Circadian Clock By Photoperiod Nuclear DNA Replication Telomere Maintenance Via Recombination Reproduction Photoperiodism Entrainment Of Circadian Clock Developmental Process Mitotic Cell Cycle Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Biosynthetic Process DNA Strand Elongation Regulation Of Viral Process
Tagcloud ?		acquisition af9 arginine biomedical bypassing cooperates critically drive drivers forming inactivating inherent lymphomagenesis lymphomas mll modulator neoplastic notch1 oncogenic overt relevance renewal revealing selectively specimen supporting suppresses sustaining transferase
Tagcloud (Difference) ?		acquisition af9 arginine biomedical bypassing cooperates critically drive drivers forming inactivating inherent lymphomagenesis lymphomas mll modulator neoplastic notch1 oncogenic overt relevance renewal revealing selectively specimen supporting suppresses sustaining transferase
Tagcloud (Intersection) ?