RBM23 and KHDC4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM23	KHDC4
Description		RNA binding motif protein 23	KH domain containing 4, pre-mRNA splicing factor
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GO Annotations	Cellular Component	Nucleus Membrane	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding U1 SnRNP Binding	RNA Binding Protein Binding
	Biological Process	MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splice Site Recognition MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		31 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 KHDC4 MAGEA11 MAGED1 MED31 OGT PGR POLA2 PRMT5 PRR20A PRR20B PRR20C PRR20D PRR20E PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 TRIM27 TUBA4A	21 interacting genes: BANP C14orf119 DNAJC5 KCNIP3 MAGEA12 NRF1 NUTF2 PIDD1 PRKAB2 PRR13 PSMB1 PUF60 QRICH1 RBM23 RBM39 RHOXF2 SAT1 SPANXN2 U2AF2 ZDHHC17 ZRSR2
Entrez ID		55147	22889
HPRD ID		15227	17198
Ensembl ID		ENSG00000100461	ENSG00000132680
Uniprot IDs		A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06	Q7Z7F0
PDB IDs		2CQ4 2DNZ	2YQR
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Rhythmic Process Regulation Of RNA Splicing Circadian Regulation Of Gene Expression Nucleoplasm Regulation Of MRNA Metabolic Process RNA Splicing Circadian Rhythm Nucleic Acid Binding Positive Regulation Of Oligodendrocyte Differentiation MRNA Processing RNA Metabolic Process Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Regulation Of RNA Metabolic Process MRNA Metabolic Process RNA Processing Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleus Estrogen Response Element Binding Positive Regulation Of Gliogenesis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Glial Cell Differentiation Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Protein-containing Complex Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of Fibroblast Proliferation Nuclear Steroid Receptor Activity Cell Development Estrogen Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Regulation Of Gliogenesis Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process Steroid Binding Photoperiodism Regulation Of Circadian Rhythm Entrainment Of Circadian Clock MRNA Binding Negative Regulation Of Hemopoiesis Negative Regulation Of Cell Development	Pre-mRNA 3'-splice Site Binding U2AF Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome U1 SnRNP Binding RNA Splicing Regulation Of RNA Splicing MRNA Processing Nucleus Nucleic Acid Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process Spermidine Binding Perforant Pathway To Dendrate Granule Cell Synapse Spermidine Acetylation Putrescine Catabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions Poly-pyrimidine Tract Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Nucleoplasm RNA Processing Diamine N-acetyltransferase Activity Protein Localization To Nuclear Pore Endopeptidase Complex Identical Protein Binding
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