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NDC80 and BLOC1S6
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NDC80
BLOC1S6
Description
NDC80 kinetochore complex component
biogenesis of lysosomal organelles complex 1 subunit 6
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Outer Kinetochore
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Centrosome
Cytosol
Membrane
Nuclear Speck
Ndc80 Complex
Stress Fiber
Ruffle
Cytoplasm
Endosome
Cytosol
Focal Adhesion
Membrane
Transport Vesicle
BLOC-1 Complex
Cytoplasmic Vesicle
Filamentous Actin
Cell-cell Contact Zone
Contractile Ring
Presynapse
Axon Cytoplasm
Microvesicle
Molecular Function
Protein Binding
Microtubule Binding
Cyclin Binding
Identical Protein Binding
Kinetochore Adaptor Activity
Protein Binding
Syntaxin Binding
Identical Protein Binding
Protein Homodimerization Activity
Actin Filament Binding
Molecular Adaptor Activity
Biological Process
Mitotic Sister Chromatid Segregation
Establishment Of Mitotic Spindle Orientation
Mitotic Cell Cycle
Nuclear Division
Spindle Organization
Mitotic Spindle Organization
Spindle Assembly Involved In Female Meiosis I
Chromosome Segregation
Mitotic Spindle Assembly Checkpoint Signaling
G2/MI Transition Of Meiotic Cell Cycle
Attachment Of Spindle Microtubules To Kinetochore
Skeletal Muscle Satellite Cell Proliferation
Regulation Of Protein Stability
Chromosome Organization
Centrosome Duplication
Cell Division
Metaphase Chromosome Alignment
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Kinetochore Organization
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Nuclear Chromosome Segregation
Kidney Development
Bradykinin Biosynthetic Process
Respiratory System Process
Endothelium Development
Amino Acid Metabolic Process
Glutamate Metabolic Process
Glutamine Metabolic Process
Protein Targeting
Lipid Metabolic Process
Phospholipid Metabolic Process
Blood Coagulation
Memory
Anterograde Axonal Transport
Protein Secretion
Response To Xenobiotic Stimulus
Gene Expression
Response To Activity
Synaptic Vesicle Docking
Dentate Gyrus Development
Hypothalamus Development
Melanocyte Differentiation
Lung Development
Neuron Projection Development
Melanosome Transport
Melanosome Organization
Positive Regulation Of Natural Killer Cell Activation
Secretion Of Lysosomal Enzymes
Intracellular Nitric Oxide Homeostasis
Multicellular Organism Growth
Endosome To Melanosome Transport
Vasodilation
Circadian Sleep/wake Cycle
Pigmentation
ATP Metabolic Process
Adenosine Metabolic Process
Intracellular Transport
Lung Alveolus Development
Anterograde Synaptic Vesicle Transport
Homeostasis Of Number Of Cells
Positive Regulation Of Pigment Cell Differentiation
Actin Filament Bundle Assembly
Lipid Homeostasis
Cilium Assembly
Membrane Fusion
Cellular Response To Epidermal Growth Factor Stimulus
Protein Transmembrane Transport
Response To Acetylcholine
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Interacting Genes
57 interacting genes:
AMOTL2
ATF4
ATP5PO
ATP6V1D
AURKA
AURKB
BLOC1S6
CAGE1
CALCOCO1
CCDC136
CCHCR1
CCNH
CCNK
CEP63
CIP2A
CKAP5
EXOC8
GOLGA2
HAUS1
HGS
IFT20
INPP1
KIFC3
KLC3
KLHL12
KRT27
KRT6B
KRT75
LNX1
MAD1L1
MAD2L1
MFAP1
MIS12
NDE1
NDEL1
NEK2
NUF2
PFDN1
PPP1R13B
PSMC2
RB1
SFR1
SKA1
SKA3
SMC1A
SPC25
STX11
TFIP11
THOC7
TOM1L1
TXLNA
USHBP1
VPS52
WASHC1
WASHC3
ZNF655
ZWINT
49 interacting genes:
ABI2
AGGF1
ANK1
APP
BLOC1S1
BLOC1S2
BLOC1S4
C4orf46
CCDC136
CCDC22
CCHCR1
CCR2
CDK5R1
CEP44
CORO6
DCTN2
DTNBP1
EPS8
EXOC8
HAUS1
IFT20
INSYN1
KRT13
KRT72
LURAP1
MED21
MLPH
NDC80
NDN
NTAQ1
NUP62
OLFM2
PLEKHA5
PLEKHF2
RABGEF1
RINT1
SKA1
SLC4A1
SMN1
SMN2
SNAPIN
STX11
STX12
STX1A
SYCE3
TPM1
TPM3
TRAK1
WASHC3
Entrez ID
10403
26258
HPRD ID
06277
16055
Ensembl ID
ENSG00000080986
ENSG00000104164
Uniprot IDs
A8K031
O14777
B3KY40
H3BST1
Q9UL45
PDB IDs
2IGP
2VE7
3IZ0
8G0P
Enriched GO Terms of Interacting Partners
?
Kinetochore
Cell Division
Chromosome, Centromeric Region
Organelle Organization
Regulation Of Mitotic Nuclear Division
Regulation Of Nuclear Division
Spindle Organization
Attachment Of Spindle Microtubules To Kinetochore
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Mitotic Sister Chromatid Separation
Chromosome Segregation
Centrosome
Regulation Of Chromosome Separation
Negative Regulation Of Cell Cycle Process
Nuclear Chromosome Segregation
Microtubule-based Process
Negative Regulation Of Cell Cycle
Microtubule Cytoskeleton Organization
Regulation Of Mitotic Metaphase/anaphase Transition
Spindle Assembly
Mitotic Sister Chromatid Segregation
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Outer Kinetochore
Sister Chromatid Segregation
Regulation Of Sister Chromatid Segregation
Spindle Pole
Cytoskeleton Organization
Regulation Of Chromosome Segregation
Mitotic Spindle Organization
Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Cytosol
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Mitotic Nuclear Division
Chromosome
Spindle
Regulation Of Chromosome Organization
Positive Regulation Of Mitotic Sister Chromatid Separation
Organelle Assembly
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Microtubule Binding
Positive Regulation Of Mitotic Sister Chromatid Segregation
Regulation Of Cell Cycle Process
Microtubule
Chromosome Organization
Membraneless Organelle Assembly
Cytoskeleton
Negative Regulation Of Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint Signaling
Regulation Of Cell Cycle
Organelle Localization
BLOC-1 Complex
Establishment Of Localization In Cell
Intracellular Transport
Cellular Localization
Axo-dendritic Transport
Organelle Organization
Establishment Of Organelle Localization
Microtubule-based Process
Establishment Of Vesicle Localization
Anterograde Synaptic Vesicle Transport
Vesicle Organization
Transport Along Microtubule
Vesicle Localization
Vesicle Transport Along Microtubule
Cytoskeleton-dependent Intracellular Transport
Microtubule-based Transport
Vesicle Cytoskeletal Trafficking
Axon Cytoplasm
Axonal Transport
Protein Transport
Establishment Of Protein Localization
Synaptic Vesicle Transport
Melanosome Organization
Pigment Granule Organization
Vesicle-mediated Transport
Anterograde Axonal Transport
Organelle Transport Along Microtubule
Intracellular Protein Localization
Cytoplasm
Cytosol
Neuron Projection
Neuron Projection Development
Regulation Of Lysosome Size
BORC Complex
Microtubule-based Movement
Exocytosis
Growth Cone
Cytoskeleton Organization
Perikaryon
Regulation Of Endosome Size
Cytoplasmic Side Of Lysosomal Membrane
Cell Projection Organization
Supramolecular Fiber Organization
Regulation Of Supramolecular Fiber Organization
Centrosome
Secretion By Cell
Regulation Of Vesicle Size
Lysosome Localization
PTB Domain Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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