NDC80 and TXLNA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NDC80	TXLNA
Gene Name		NDC80 kinetochore complex component	taxilin alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleus Cytosol Membrane Ndc80 Complex	Extracellular Region Cytoplasm Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Cytokine Activity Protein Binding Syntaxin Binding High Molecular Weight B Cell Growth Factor Receptor Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore	Exocytosis Cell Proliferation B Cell Activation
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		45 interactors: AMOTL2 ATF4 ATP5O AURKA AURKB BLOC1S6 CALCOCO1 CCDC101 CCDC53 CCHCR1 CCNH CCNK CENPH HAUS1 HGS IFT20 INPP1 KLC3 KLHL12 KRT6B MAD1L1 MAD2L1 MED4 MFAP1 MIS12 NDE1 NDEL1 NEK2 NUF2 PFDN1 PSMC2 RB1 RUFY4 SFR1 SKA1 SMC1A SPC25 STX11 TFIP11 TNIP1 TOM1L1 TP53BP2 TXLNA USHBP1 ZWINT	53 interactors: AZI2 BRCA1 BTF3 BTF3L4 CCDC136 CCDC53 CCDC67 CCHCR1 CDR2 CEP44 CEP57L1 CEP63 DTNB EIF4ENIF1 GOLGA2 GORASP2 HAUS3 HYPK IKBKG KANK2 KRT13 KRT15 KRT20 KRT31 KRT38 KRT40 LCA5 MBIP MED4 MEOX1 MEOX2 NACA NDC80 NMI NSMCE2 NUP62 PPFIA1 RCOR3 RINT1 SMARCE1 SPERT STMN2 STX1A STX3 STX4 TBK1 TCL1A TFIP11 TNIP1 TP53BP2 TXLNB USHBP1 VPS52
Entrez ID		10403	200081
HPRD ID		06277	09408
Ensembl ID		ENSG00000080986	ENSG00000084652
Uniprot IDs		A8K031 O14777	P40222
PDB IDs		2IGP 2VE7 3IZ0
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Division Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Division Cell Cycle Chromosome Segregation Cell Cycle Process Negative Regulation Of Cell Cycle Centrosome Separation Organelle Organization Regulation Of Cell Cycle Microtubule-based Process Regulation Of Cell Cycle Process Mitotic Spindle Organization Regulation Of Mitotic Cell Cycle Cellular Localization Mitotic Centrosome Separation Microtubule Cytoskeleton Organization Regulation Of Mitotic Nuclear Division Centrosome Localization Spindle Organization Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Mitotic Sister Chromatid Segregation Regulation Of Chromosome Segregation Mitotic Cell Cycle Checkpoint Sister Chromatid Segregation Centrosome Organization Organelle Localization Establishment Of Localization In Cell Microtubule Organizing Center Organization Centrosome Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Transport Chromosome Organization Negative Regulation Of Cell Division Spindle Assembly Organelle Assembly Spindle Stabilization Cytoskeleton Organization Protein Localization To Chromosome Establishment Of Organelle Localization Regulation Of Organelle Organization Establishment Of Vesicle Localization Protein Localization To Organelle	Synaptic Vesicle Fusion To Presynaptic Membrane Dendritic Cell Proliferation Organelle Organization Protein Localization Cell Cycle Protein Transport Establishment Of Protein Localization Mitotic Cell Cycle Neurotransmitter Secretion Somite Specification Positive Regulation Of Protein Localization To Cell Surface Regulation Of Neurotransmitter Levels Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis I-kappaB Kinase/NF-kappaB Signaling Neurotransmitter Transport Establishment Of Organelle Localization Microtubule-based Process Type I Interferon Production Developmental Process Organelle Fusion Centriole Assembly Positive Regulation Of Transcription, DNA-templated Vesicle Docking Establishment Of Vesicle Localization Establishment Of Localization In Cell Segment Specification Interferon-gamma Production Vesicle Localization Cellular Localization Centrosome Organization Membrane Docking Regulation Of Protein Localization To Cell Surface Regulation Of I-kappaB Kinase/NF-kappaB Signaling Organelle Localization Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Glutamate Secretion Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor Signaling Pathway Synaptic Vesicle Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Synaptic Transmission Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Spindle Organization Membrane Fusion Pattern Recognition Receptor Signaling Pathway
Tagcloud ?		assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mis12 mitosis orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Difference) ?		assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mis12 mitosis orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Intersection) ?