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BLOC1S6 and STX11
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
BLOC1S6
STX11
Description
biogenesis of lysosomal organelles complex 1 subunit 6
syntaxin 11
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Ruffle
Cytoplasm
Endosome
Cytosol
Focal Adhesion
Membrane
Transport Vesicle
BLOC-1 Complex
Cytoplasmic Vesicle
Filamentous Actin
Cell-cell Contact Zone
Contractile Ring
Presynapse
Axon Cytoplasm
Microvesicle
Golgi Apparatus
Plasma Membrane
Endomembrane System
Membrane
SNARE Complex
Presynaptic Active Zone Membrane
Molecular Function
Protein Binding
Syntaxin Binding
Identical Protein Binding
Protein Homodimerization Activity
Actin Filament Binding
Molecular Adaptor Activity
SNARE Binding
SNAP Receptor Activity
Protein Binding
Biological Process
Kidney Development
Bradykinin Biosynthetic Process
Respiratory System Process
Endothelium Development
Amino Acid Metabolic Process
Glutamate Metabolic Process
Glutamine Metabolic Process
Protein Targeting
Lipid Metabolic Process
Phospholipid Metabolic Process
Blood Coagulation
Memory
Anterograde Axonal Transport
Protein Secretion
Response To Xenobiotic Stimulus
Gene Expression
Response To Activity
Synaptic Vesicle Docking
Dentate Gyrus Development
Hypothalamus Development
Melanocyte Differentiation
Lung Development
Neuron Projection Development
Melanosome Transport
Melanosome Organization
Positive Regulation Of Natural Killer Cell Activation
Secretion Of Lysosomal Enzymes
Intracellular Nitric Oxide Homeostasis
Multicellular Organism Growth
Endosome To Melanosome Transport
Vasodilation
Circadian Sleep/wake Cycle
Pigmentation
ATP Metabolic Process
Adenosine Metabolic Process
Intracellular Transport
Lung Alveolus Development
Anterograde Synaptic Vesicle Transport
Homeostasis Of Number Of Cells
Positive Regulation Of Pigment Cell Differentiation
Actin Filament Bundle Assembly
Lipid Homeostasis
Cilium Assembly
Membrane Fusion
Cellular Response To Epidermal Growth Factor Stimulus
Protein Transmembrane Transport
Response To Acetylcholine
Intracellular Protein Transport
Exocytosis
Protein Transport
Vesicle-mediated Transport
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Membrane Fusion
Pathways
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS
Nicotine dependence symptom count (
25555482
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Interacting Genes
49 interacting genes:
ABI2
AGGF1
ANK1
APP
BLOC1S1
BLOC1S2
BLOC1S4
C4orf46
CCDC136
CCDC22
CCHCR1
CCR2
CDK5R1
CEP44
CORO6
DCTN2
DTNBP1
EPS8
EXOC8
HAUS1
IFT20
INSYN1
KRT13
KRT72
LURAP1
MED21
MLPH
NDC80
NDN
NTAQ1
NUP62
OLFM2
PLEKHA5
PLEKHF2
RABGEF1
RINT1
SKA1
SLC4A1
SMN1
SMN2
SNAPIN
STX11
STX12
STX1A
SYCE3
TPM1
TPM3
TRAK1
WASHC3
98 interacting genes:
AIRIM
APP
AXIN1
AXIN2
BLOC1S6
BYSL
CARD9
CCBE1
CCDC120
CCDC125
CCDC184
CCDC196
CCDC33
CCHCR1
CCNK
CDCA7L
CDR2L
CRYBA4
CTBP2
CWF19L2
DISC1
DUSP29
EIF1AD
EIF2B5
FAM110A
FAM161A
FAM161B
FAM74A4
FAM90A1
FARS2
GOLGA8EP
GOLGA8F
HAUS1
HGS
HOXA1
IKBKG
IKZF3
KAT5
KCTD9
KDM1A
KIFC3
KLC3
KRT75
KXD1
LENG1
LONRF1
MAGOHB
MBD3L1
MBIP
MEOX2
MFAP1
MID2
MIS18A
MTCL2
NDC80
NTAQ1
PKN1
PPP1R18
PRKAB2
PRPF18
PRPF31
PSMA3
PSMC3
RAD51D
RNF6
RNF8
RNPS1
RUNX1T1
SCNM1
SH2D4A
SHC3
SIKE1
SLC38A2
SMARCE1
SNAP23
SNAP25
SNCA
SNX3
STX1A
STX4
SUV39H1
TADA3
TAF6L
TBK1
TCEA2
TCF4
TLE5
TNFRSF21
TRIM41
TSGA10IP
UBASH3A
USHBP1
VAMP2
VPS52
ZCCHC10
ZNF19
ZNF417
ZNF587
Entrez ID
26258
8676
HPRD ID
16055
09231
Ensembl ID
ENSG00000104164
ENSG00000135604
Uniprot IDs
B3KY40
H3BST1
Q9UL45
O75558
PDB IDs
Enriched GO Terms of Interacting Partners
?
Organelle Localization
BLOC-1 Complex
Establishment Of Localization In Cell
Intracellular Transport
Cellular Localization
Axo-dendritic Transport
Organelle Organization
Establishment Of Organelle Localization
Microtubule-based Process
Establishment Of Vesicle Localization
Anterograde Synaptic Vesicle Transport
Vesicle Organization
Transport Along Microtubule
Vesicle Localization
Vesicle Transport Along Microtubule
Cytoskeleton-dependent Intracellular Transport
Microtubule-based Transport
Vesicle Cytoskeletal Trafficking
Axon Cytoplasm
Axonal Transport
Protein Transport
Establishment Of Protein Localization
Synaptic Vesicle Transport
Melanosome Organization
Pigment Granule Organization
Vesicle-mediated Transport
Anterograde Axonal Transport
Organelle Transport Along Microtubule
Intracellular Protein Localization
Cytoplasm
Cytosol
Neuron Projection
Neuron Projection Development
Regulation Of Lysosome Size
BORC Complex
Microtubule-based Movement
Exocytosis
Growth Cone
Cytoskeleton Organization
Perikaryon
Regulation Of Endosome Size
Cytoplasmic Side Of Lysosomal Membrane
Cell Projection Organization
Supramolecular Fiber Organization
Regulation Of Supramolecular Fiber Organization
Centrosome
Secretion By Cell
Regulation Of Vesicle Size
Lysosome Localization
PTB Domain Binding
Identical Protein Binding
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
SNARE Complex Assembly
Protein Binding
SNAP Receptor Activity
SNARE Complex
Synaptic Vesicle Docking
Synaptic Vesicle Exocytosis
SNARE Binding
Regulation Of Cellular Response To Stress
Regulation Of DNA Repair
BLOC-1 Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex
Synaptic Vesicle Priming
Establishment Of Localization In Cell
Membrane Docking
Establishment Of Organelle Localization
Positive Regulation Of Proteolysis
Positive Regulation Of Synaptic Transmission
Syntaxin Binding
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Regulation Of RNA Metabolic Process
Transcription Coactivator Activity
Neurotransmitter Transport
Vesicle Fusion
Membrane Fusion
Long-term Synaptic Potentiation
Regulation Of Gene Expression
Organelle Membrane Fusion
Organelle Localization
Establishment Of Vesicle Localization
Host-mediated Perturbation Of Symbiont Process
DNA Repair-dependent Chromatin Remodeling
Regulation Of DNA-templated Transcription
Nuclear Androgen Receptor Binding
Vesicle Organization
Vesicle Docking
Regulation Of RNA Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Modulation Of Process Of Another Organism
Microtubule-based Process
Vesicle Localization
Neuron Projection
Nucleoplasm
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Tagcloud (Difference)
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Tagcloud (Intersection)
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