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NDC80 and HAUS1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
NDC80
HAUS1
Description
NDC80 kinetochore complex component
HAUS augmin like complex subunit 1
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Outer Kinetochore
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Centrosome
Cytosol
Membrane
Nuclear Speck
Ndc80 Complex
Spindle Pole
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Microtubule
HAUS Complex
Mitotic Spindle Microtubule
Molecular Function
Protein Binding
Microtubule Binding
Cyclin Binding
Identical Protein Binding
Kinetochore Adaptor Activity
Protein Binding
Biological Process
Mitotic Sister Chromatid Segregation
Establishment Of Mitotic Spindle Orientation
Mitotic Cell Cycle
Nuclear Division
Spindle Organization
Mitotic Spindle Organization
Spindle Assembly Involved In Female Meiosis I
Chromosome Segregation
Mitotic Spindle Assembly Checkpoint Signaling
G2/MI Transition Of Meiotic Cell Cycle
Attachment Of Spindle Microtubules To Kinetochore
Skeletal Muscle Satellite Cell Proliferation
Regulation Of Protein Stability
Chromosome Organization
Centrosome Duplication
Cell Division
Metaphase Chromosome Alignment
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Kinetochore Organization
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Nuclear Chromosome Segregation
Centrosome Cycle
Regulation Of Microtubule Nucleation
Spindle Assembly
Cell Division
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Interacting Genes
57 interacting genes:
AMOTL2
ATF4
ATP5PO
ATP6V1D
AURKA
AURKB
BLOC1S6
CAGE1
CALCOCO1
CCDC136
CCHCR1
CCNH
CCNK
CEP63
CIP2A
CKAP5
EXOC8
GOLGA2
HAUS1
HGS
IFT20
INPP1
KIFC3
KLC3
KLHL12
KRT27
KRT6B
KRT75
LNX1
MAD1L1
MAD2L1
MFAP1
MIS12
NDE1
NDEL1
NEK2
NUF2
PFDN1
PPP1R13B
PSMC2
RB1
SFR1
SKA1
SKA3
SMC1A
SPC25
STX11
TFIP11
THOC7
TOM1L1
TXLNA
USHBP1
VPS52
WASHC1
WASHC3
ZNF655
ZWINT
82 interacting genes:
AK8
ARFIP2
ATP6V1D
BFSP2
BLOC1S6
BORCS6
C3orf62
CAGE1
CBY2
CCDC136
CCDC57
CCHCR1
CDR2
CENPP
CEP170P1
CEP44
CEP55
CEP57L1
CEP63
CEP70
DCTN2
DMD
DTNBP1
FAM161B
FGFR1OP2
GOLGA2
HGS
HOOK2
IFIT3
IFT20
INCA1
KDM1A
KIFC3
KRT1
KRT15
KRT18
KRT19
KRT3
KRT31
KRT38
KRT40
KXD1
LDOC1
LURAP1
MAD1L1
MAGEA6
MCM10
MCM3
MED4
MED7
MIPOL1
MTUS2
NDC80
NECAB2
NINL
NUP54
NUP62
ODAD1
PDE4DIP
PIBF1
PKN1
POLR3C
SPAG5
SSC5D
STX11
SYCE1
SYCE3
TEAD4
TFIP11
TFPT
TRAF1
TRIM23
TRIM27
TRIM54
TRIM69
TSG101
TXN2
USHBP1
VPS37C
VPS52
WASHC3
ZNF471
Entrez ID
10403
115106
HPRD ID
06277
16385
Ensembl ID
ENSG00000080986
ENSG00000152240
Uniprot IDs
A8K031
O14777
Q96CS2
PDB IDs
2IGP
2VE7
3IZ0
8G0P
7SQK
Enriched GO Terms of Interacting Partners
?
Kinetochore
Cell Division
Chromosome, Centromeric Region
Organelle Organization
Regulation Of Mitotic Nuclear Division
Regulation Of Nuclear Division
Spindle Organization
Attachment Of Spindle Microtubules To Kinetochore
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Mitotic Sister Chromatid Separation
Chromosome Segregation
Centrosome
Regulation Of Chromosome Separation
Negative Regulation Of Cell Cycle Process
Nuclear Chromosome Segregation
Microtubule-based Process
Negative Regulation Of Cell Cycle
Microtubule Cytoskeleton Organization
Regulation Of Mitotic Metaphase/anaphase Transition
Spindle Assembly
Mitotic Sister Chromatid Segregation
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Outer Kinetochore
Sister Chromatid Segregation
Regulation Of Sister Chromatid Segregation
Spindle Pole
Cytoskeleton Organization
Regulation Of Chromosome Segregation
Mitotic Spindle Organization
Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Cytosol
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Mitotic Nuclear Division
Chromosome
Spindle
Regulation Of Chromosome Organization
Positive Regulation Of Mitotic Sister Chromatid Separation
Organelle Assembly
Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Microtubule Binding
Positive Regulation Of Mitotic Sister Chromatid Segregation
Regulation Of Cell Cycle Process
Microtubule
Chromosome Organization
Membraneless Organelle Assembly
Cytoskeleton
Negative Regulation Of Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint Signaling
Regulation Of Cell Cycle
Cytoskeleton
Organelle Organization
Centrosome
Microtubule-based Process
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Cytoskeleton Organization
Intermediate Filament Organization
Protein Binding
Structural Constituent Of Skin Epidermis
Keratin Filament
Organelle Assembly
Intermediate Filament
Identical Protein Binding
Microtubule Organizing Center Organization
Establishment Of Localization In Cell
Supramolecular Fiber Organization
Organelle Localization
Intracellular Transport
Centrosome Cycle
Microtubule Binding
Intracellular Protein Localization
Protein Localization To Centrosome
Metaphase Chromosome Alignment
Cellular Component Assembly
Protein Transport
Cilium Organization
Centriole Assembly
Spindle Organization
Cellular Localization
Structural Molecule Activity
Establishment Of Protein Localization
Cilium Assembly
Microtubule
Establishment Of Organelle Localization
Chromosome Localization
BLOC-1 Complex
Plasma Membrane Bounded Cell Projection Assembly
Microtubule Cytoskeleton Organization
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cell Projection Assembly
Mitotic Metaphase Chromosome Alignment
Protein Localization To Cytoskeleton
Spindle Pole
Structural Constituent Of Cytoskeleton
Vesicle Organization
Centriole
Centriole Replication
Protein Localization To Organelle
Endosomal Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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