BLOC1S6 and CCDC136

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BLOC1S6	CCDC136
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex	Mitochondrion Integral Component Of Membrane
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Organization Membrane Fusion
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCDC53 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WDYHV1	62 interactors: ABT1 AQP1 ASB7 ATP5O ATXN1 BARD1 BLOC1S6 BYSL C19orf66 C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZSCAN26
Entrez ID		26258	64753
HPRD ID		16055	10887
Ensembl ID		ENSG00000104164	ENSG00000128596
Uniprot IDs		B3KY40 Q9UL45	Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Axon Cargo Transport Melanosome Organization Pigment Granule Organization Organelle Organization Cellular Pigmentation Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Organelle Localization Synaptic Vesicle Transport Movement Of Cell Or Subcellular Component Establishment Of Vesicle Localization Intracellular Transport Pigmentation Vesicle Organization Establishment Of Organelle Localization Vesicle Localization Membrane Organization Neuron Development Microtubule-based Process Neuron Projection Development Platelet Dense Granule Organization Microtubule-based Movement Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Vesicle-mediated Transport Protein Localization Protein Transport Establishment Of Protein Localization Cell Development Post-Golgi Vesicle-mediated Transport Generation Of Neurons Cellular Protein Localization Neurogenesis Neuron Recognition Secretory Granule Organization Transport Endomembrane System Organization Golgi Vesicle Transport Vesicle Fusion Nervous System Development Mitotic Nuclear Division Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Organelle Fusion	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Chromatin Organization Chromatin Modification Cellular Metabolic Process Organelle Organization Cell Cycle Regulation Of Cellular Process Chromosome Organization Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Sumoylation Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Catabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host 'de Novo' Actin Filament Nucleation Transepithelial Water Transport Cardiac Muscle Thin Filament Assembly
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