BLOC1S6 and BLOC1S1

Number of citations of the paper that reports this interaction (PubMedID 15102850)
0

Data Source:
HPRD (two hybrid)

		BLOC1S6	BLOC1S1
Description		biogenesis of lysosomal organelles complex 1 subunit 6	biogenesis of lysosomal organelles complex 1 subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Ruffle Cytoplasm Endosome Cytosol Focal Adhesion Membrane Transport Vesicle BLOC-1 Complex Cytoplasmic Vesicle Filamentous Actin Cell-cell Contact Zone Contractile Ring Presynapse Axon Cytoplasm Microvesicle	Extracellular Space Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosome Lysosomal Membrane Early Endosome Cytosol Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding Molecular Adaptor Activity	Protein Binding Transferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process	Kidney Development Bradykinin Biosynthetic Process Respiratory System Process Endothelium Development Amino Acid Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Protein Targeting Lipid Metabolic Process Phospholipid Metabolic Process Blood Coagulation Memory Anterograde Axonal Transport Protein Secretion Response To Xenobiotic Stimulus Gene Expression Response To Activity Synaptic Vesicle Docking Dentate Gyrus Development Hypothalamus Development Melanocyte Differentiation Lung Development Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Intracellular Nitric Oxide Homeostasis Multicellular Organism Growth Endosome To Melanosome Transport Vasodilation Circadian Sleep/wake Cycle Pigmentation ATP Metabolic Process Adenosine Metabolic Process Intracellular Transport Lung Alveolus Development Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Positive Regulation Of Pigment Cell Differentiation Actin Filament Bundle Assembly Lipid Homeostasis Cilium Assembly Membrane Fusion Cellular Response To Epidermal Growth Factor Stimulus Protein Transmembrane Transport Response To Acetylcholine	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways		Golgi Associated Vesicle Biogenesis	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		49 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3	18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1
Entrez ID		26258	2647
HPRD ID		16055	03263
Ensembl ID		ENSG00000104164	ENSG00000135441
Uniprot IDs		B3KY40 H3BST1 Q9UL45	P78537
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Localization BLOC-1 Complex Establishment Of Localization In Cell Intracellular Transport Cellular Localization Axo-dendritic Transport Organelle Organization Establishment Of Organelle Localization Microtubule-based Process Establishment Of Vesicle Localization Anterograde Synaptic Vesicle Transport Vesicle Organization Transport Along Microtubule Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Cytoskeletal Trafficking Axon Cytoplasm Axonal Transport Protein Transport Establishment Of Protein Localization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Vesicle-mediated Transport Anterograde Axonal Transport Organelle Transport Along Microtubule Intracellular Protein Localization Cytoplasm Cytosol Neuron Projection Neuron Projection Development Regulation Of Lysosome Size BORC Complex Microtubule-based Movement Exocytosis Growth Cone Cytoskeleton Organization Perikaryon Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Cell Projection Organization Supramolecular Fiber Organization Regulation Of Supramolecular Fiber Organization Centrosome Secretion By Cell Regulation Of Vesicle Size Lysosome Localization PTB Domain Binding	Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axo-dendritic Transport Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Anterograde Axonal Transport Vesicle Transport Along Microtubule Establishment Of Vesicle Localization Vesicle Cytoskeletal Trafficking Vesicle Localization Axon Cytoplasm Axonal Transport Organelle Transport Along Microtubule Transport Along Microtubule Neuron Projection Development Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Establishment Of Organelle Localization Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Vesicle Organization Plasma Membrane Bounded Cell Projection Organization Microtubule-based Movement Microvesicle Endosome To Melanosome Transport Organelle Localization Cell Projection Organization Microtubule-based Process Cellular Localization Establishment Of Localization In Cell Intracellular Transport Secretion Of Lysosomal Enzymes Pigmentation Positive Regulation Of Pigment Cell Differentiation Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Regulation Of Endosome Size Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Stem Cell Differentiation Cytoplasmic Side Of Lysosomal Membrane Regulation Of Developmental Pigmentation Developmental Pigmentation Chromatin Binding Rhythmic Process Regulation Of Vesicle Size
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