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BMI1 and CEP126
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
BMI1
CEP126
Description
BMI1 proto-oncogene, polycomb ring finger
centrosomal protein 126
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Heterochromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Body
PcG Protein Complex
PRC1 Complex
Cytoplasm
Centrosome
Cytoskeleton
Midbody
Cell Projection
Ciliary Base
Molecular Function
Chromatin Binding
Protein Binding
Zinc Ion Binding
Metal Ion Binding
RING-like Zinc Finger Domain Binding
Ubiquitin-protein Transferase Activator Activity
Promoter-specific Chromatin Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal System Development
In Utero Embryonic Development
Chromatin Organization
Chromatin Remodeling
DNA Methylation-dependent Constitutive Heterochromatin Formation
Humoral Immune Response
Segment Specification
Brain Development
Regulation Of Gene Expression
Rostrocaudal Neural Tube Patterning
Hemopoiesis
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Immature T Cell Proliferation In Thymus
Negative Regulation Of Gene Expression, Epigenetic
Somatic Stem Cell Division
Positive Regulation Of Fibroblast Proliferation
Embryonic Skeletal System Morphogenesis
Embryonic Skeletal System Development
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Interleukin-1
Cellular Response To Dexamethasone Stimulus
Regulation Of Kidney Development
Apoptotic Signaling Pathway
Regulation Of Adaxial/abaxial Pattern Formation
Negative Regulation Of Apoptotic Signaling Pathway
Mitotic Spindle Organization
Cell Projection Organization
Cytoplasmic Microtubule Organization
Cilium Assembly
Non-motile Cilium Assembly
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Drugs
Diseases
Penile cancer
GWAS
Prostate-specific antigen levels (
28139693
)
Interacting Genes
45 interacting genes:
CASC9
CBX8
CEP126
CSNK2B
DEFA5
E2F6
FOXS1
H2AC18
H2AC20
H2AC4
H2AX
H2BC3
H3-4
HSF2BP
IMMT
KAT5
KMT2A
LRIF1
MAPK14
MLLT1
MUC1
NDEL1
PCBP2-OT1
PCGF3
PCGF6
PGR
PHC1
PHC2
PTN
RBM22
RING1
RNF114
RNF2
RRM1
SOCS2
TRIM27
TUSC3
UBE2D2
UBE2D3
UBE2I
USP11
USP15
VPS11
WHRN
ZBTB16
87 interacting genes:
AIMP2
AKTIP
ARIH2
ATP6V1F
ATRX
BMI1
BRD1
C11orf58
CDKN2B
CRCT1
CSTF2
DGCR6
DISC1
DLEU1
DNM1
DUSP12
DUSP23
EIF2S2
EIF6
EPN1
FAM118B
FAM200C
FEZ1
FGFR3
FXR1
GEMIN7
GET4
GIT1
GOLGB1
GPRASP2
GSTO1
HMOX2
HTT
ING5
KAT5
KAT7
KIF15
KLHL20
LAMTOR5
LPL
LRRC1
LUC7L2
MAD2L1BP
MAPK9
MLH1
MRPS6
NAP1L5
NAT9
NPM3
NSF
NUDT21
ODF2L
OFD1
PBK
PDCD5
PFDN1
PIK3R3
PMF1
POLD1
POLR2M
PPP1CA
PPP1CC
PRKRA
PTPRS
RAB27A
RAN
RBM23
RETREG2
RGS2
RIF1
ROGDI
RPA2
RUVBL1
SAT1
SNRPG
SPDL1
STAU2
TFG
TNFRSF14
TNFSF11
TOMM20
TTR
TXNDC9
VIM
YAE1
YWHAZ
ZNF24
Entrez ID
648
57562
HPRD ID
01277
17212
Ensembl ID
ENSG00000168283
ENSG00000110318
Uniprot IDs
P35226
Q9P2H0
PDB IDs
2H0D
2NA1
3RPG
4R8P
5FR6
6WI7
6WI8
7ND1
8GRM
8PP7
9DBY
9DDE
9DGG
Enriched GO Terms of Interacting Partners
?
PcG Protein Complex
PRC1 Complex
Chromatin Remodeling
Chromatin Organization
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleosome
Epigenetic Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Metabolic Process
Structural Constituent Of Chromatin
Chromosome
Post-translational Protein Modification
Negative Regulation Of Gene Expression, Epigenetic
Protein Modification Process
Nucleoplasm
Sex Chromatin
Protein Modification By Small Protein Conjugation
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Metabolic Process
Heterochromatin Formation
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Ubiquitination
Chromatin Binding
Nucleus
Regulation Of Gene Expression
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Heterochromatin
Regulation Of Metabolic Process
RING-like Zinc Finger Domain Binding
Ubiquitin Protein Ligase Activity
Histone H2AK119 Ubiquitin Ligase Activity
Regulation Of DNA-templated Transcription
Regulation Of RNA Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
MLL1 Complex
Developmental Process Involved In Reproduction
Regulation Of Primary Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
PML Body
Protein Metabolic Process
Ubiquitin-protein Transferase Activator Activity
Protein Heterodimerization Activity
Zinc Ion Binding
Nuclear Body
Response To Ionizing Radiation
Signal Transduction In Response To DNA Damage
Nucleus
Organelle Organization
Cytosol
Histone H3-K14 Acetyltransferase Complex
Protein Binding
Establishment Of Organelle Localization
Phosphoprotein Phosphatase Activity
Microtubule Cytoskeleton Organization Involved In Mitosis
Protein-RNA Complex Assembly
DNA Replication-dependent Chromatin Disassembly
Organelle Localization
Cytoplasm
Chromatin Binding
Presynapse
Axon
Positive Regulation Of Aggrephagy
Histone Acetyltransferase Complex
DNA Repair
Chromosome, Telomeric Region
Regulation Of Circadian Rhythm
Chromosome Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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