PCGF3 and CBX6

Number of citations of the paper that reports this interaction (PMID 21282530)
11

Data Source:
BioGRID (pull down)

		PCGF3	CBX6
Gene Name		polycomb group ring finger 3	chromobox homolog 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex
	Molecular Function	Protein Binding Zinc Ion Binding	Single-stranded RNA Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Chromatin Modification
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Hemostatic factors and hematological phenotypes ( 22443383)	Bladder cancer ( 20972438)
Protein-Protein Interactions		12 interactors: BCOR BCORL1 BMI1 CBX6 CBX7 CBX8 DZIP3 PHC2 RING1 RNF2 TRIM9 UBE2C	9 interactors: BMI1 HOXC9 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 RING1 RNF2
Entrez ID		10336	23466
HPRD ID		11515	13005
Ensembl ID		ENSG00000185619	ENSG00000183741
Uniprot IDs		B3KWT8 Q3KNV8	B0QXZ6 O95503
PDB IDs			3GV6 3I90
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Chromatin Organization Chromosome Organization Histone H2A Monoubiquitination Histone H2A Ubiquitination Histone Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Protein Monoubiquitination Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Organelle Organization Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Gene Expression Pattern Specification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Anterior/posterior Pattern Specification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Heterocycle Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Ligase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Free Ubiquitin Chain Polymerization Negative Regulation Of Tooth Mineralization Negative Regulation Of SNARE Complex Assembly	Histone Ubiquitination Transcription, DNA-templated RNA Biosynthetic Process Histone H2A Monoubiquitination Histone H2A Ubiquitination Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Histone Monoubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Pattern Specification Process Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Ubiquitination Chromatin Modification Protein Modification By Small Protein Conjugation Nitrogen Compound Metabolic Process Chromatin Organization Embryonic Skeletal System Morphogenesis Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryonic Skeletal System Development Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Embryonic Morphogenesis Skeletal System Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Morphogenesis Organ Morphogenesis Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Embryo Development Embryonic Organ Development Histone H2A-K119 Monoubiquitination Histone Acetylation
Tagcloud ?			acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax
Tagcloud (Difference) ?			acetylase aldh1a3 belonging bipotent ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico smarca4 smarcd3 smarce1 subpopulations trithorax
Tagcloud (Intersection) ?