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CBX6
Description
chromobox 6
Image
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
Chromosome
Nuclear Body
PcG Protein Complex
PRC1 Complex
Molecular Function
Chromatin Binding
Single-stranded RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Pathways
Oxidative Stress Induced Senescence
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Bladder cancer (
20972438
24163127
)
Plateletcrit (
32888494
)
Interacting Genes
7 interacting genes:
H3-3A
H3C1
H3C14
HOXC9
PCGF2
PCGF6
RNF2
Entrez ID
23466
HPRD ID
13005
Ensembl ID
ENSG00000183741
Uniprot IDs
B0QXZ6
O95503
PDB IDs
3GV6
3I90
Enriched GO Terms of Interacting Partners
?
Chromatin Remodeling
PRC1 Complex
Chromatin Organization
PcG Protein Complex
Sex Chromatin
Structural Constituent Of Chromatin
Nucleosome Assembly
Nucleosome
Nucleosome Organization
Nucleoplasm
Protein-DNA Complex Assembly
Chromosome
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Epigenetic Regulation Of Gene Expression
Gene Expression
Embryonic Skeletal System Development
Protein Heterodimerization Activity
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Metabolic Process
Pattern Specification Process
DNA Binding
Chromatin
Embryonic Skeletal System Morphogenesis
Embryonic Morphogenesis
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Chromatin Binding
Nucleus
Skeletal System Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Telomere Organization
Embryonic Organ Morphogenesis
Negative Regulation Of Macromolecule Metabolic Process
RING-like Zinc Finger Domain Binding
Negative Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Chromosome Condensation
Histone H2AK119 Ubiquitin Ligase Activity
Negative Regulation Of Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Anterior/posterior Pattern Specification
Pericentric Heterochromatin Formation
Regulation Of Centromere Complex Assembly
Skeletal System Development
Germ Cell Development
Barr Body
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